Recombinant Human GGPS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GGPS1-1260H
• Product Overview: GGPS1 MS Standard C13 and N15-labeled recombinant protein (NP_001032354) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.9 kDa
• AA Sequence: MEKTQETVQRILLEPYKYLLQLPGK QVRTKLSQAFNHWLKVPEDKLQIII EVTEMLHNASLLIDDIEDNSKLRRG FPVAHSIYGIPSVINSANYVYFLGL EKVLTLDHPDAVKLFTRQLLELHQG QGLDIYWRDNYTCPTEEEYKAMVLQ KTGGLFGLAVGLMQLFSDYKEDLKP LLNTLGLFFQIRDDYANLHSKEYSE NKSFCEDLTEGKFSFPTIHAIWSRP ESTQVQNILRQRTENIDIKKYCVHY LEDVGSFEYTRNTLKELEAKAYKQI DARGGNPELVALVKHLSKMFKEENE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GGPS1 geranylgeranyl diphosphate synthase 1 [ Homo sapiens (human) ]
• Official Symbol: GGPS1
• Synonyms: GGPS1; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; GGPPS1; GGPPSase; GGPP synthase; geranyltranstransferase; farnesyltranstransferase; dimethylallyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosphate synthase; GGPPS
• Gene ID: 9453
• mRNA Refseq: NM_001037277
• Protein Refseq: NP_001032354
• MIM: 606982
• UniProt ID: O95749