gp9
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  • Official Full Name
  • glycoprotein IX (platelet)
  • Background
  • This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
  • Synonyms
  • GPIX; CD42a; GP9 platelet glycoprotein IX; GP-IX; glycoprotein 9; OTTHUMP00000217111
Cat.#:GP9-5133HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GP9 Protein, GST-tagged
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Cat.#:GP9-26632THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GP9
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Cat.#:GP9-7219HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GP9, His-tagged
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Cat.#:GP9-7085MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GP9 Protein
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Cat.#:GP9-1925RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GP9 Protein, His-tagged
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Cat.#:GP9-5820HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GP9 293 Cell Lysate
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Involved Pathway

GP9 involved in several pathways and played different roles in them. We selected most pathways GP9 participated on our site, such as ECM-receptor interaction, Platelet activation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with GP9 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ECM-receptor interaction
ITGA4; LAMC1; COL1A1; ITGB6; ITGB1B.2; COL1A1A; THBS3; ITGA8; ITGA3; LAMA5
Platelet activation
Adcy4; RHOA; PIK3R1; PPP1CA; PRKCZ; PRKACA; PPP1R12A; ITGA2B; PRKACG; PLA2G4D
Hematopoietic cell lineage
ITGA2B; GM2002; CD1C; Cd24a; FCER2; CD3D; ITGA2; IL11RA2; CSF3R; CD4

Protein Function

GP9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GP9 itself. We selected most functions GP9 had, and list some proteins which have the same functions with GP9. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein DVL2; TRAF7; RPA2; ALOX15; PCSK5; STXBP2; ITGB1BP1; JAKMIP2; ALKBH4; UBAP1

Interacting Protein

GP9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GP9 here. Most of them are supplied by our site. Hope this information will be useful for your research of GP9.
SPRY2; GP1BA; HOXA1; GP5; APPBP2; CRK; Hoxa1; GP1BB

GP9 Related Articles

Bragadottir, G; Birgisdottir, ER; et al. Clinical phenotype in heterozygote and biallelic Bernard-Soulier syndrome-A case control study. AMERICAN JOURNAL OF HEMATOLOGY 90:149-155(2015).
Hassapis, KA; Stylianou, DC; et al. Architectural Insight into Inovirus-Associated Vectors (IAVs) and Development of IAV-Based Vaccines Inducing Humoral and Cellular Responses: Implications in HIV-1 Vaccines. VIRUSES-BASEL 6:5047-5076(2014).