GPR143 Protein, G protein-coupled receptor 143

GPR143

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GPR143

Official Full Name G protein-coupled receptor 143
Background This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.
Synonyms GPR143; G protein-coupled receptor 143; OA1, ocular albinism 1 (Nettleship Falls); G-protein coupled receptor 143; ocular albinism 1 (Nettleship Falls); ALBINISM OCULAR TYPE I; G protein coupled receptor 143; GP143_HUMAN; MOA1; NETTLESHIP FALLS TYPE OCULAR ALBINISM; Ocular albinism type 1 protein; Ocular albinism type 1 protein homolog; Ocular albinism1 Nettleship Falls type; OA1; NYS6
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GPR143-5188H Recombinant Human GPR143 Protein Wheat Germ N/A
    Human GPR143-5189H Recombinant Human GPR143 Protein, GST-tagged Wheat Germ GST
    Human GPR143-739HCL Recombinant Human GPR143 cell lysate N/A
    Mouse GPR143-7148M Recombinant Mouse GPR143 Protein Mammalian Cell His
    Chicken GPR143-5107C Recombinant Chicken GPR143 Mammalian Cell His
    Zebrafish GPR143-11078Z Recombinant Zebrafish GPR143 Mammalian Cell His
    Kit-1287 GPR143 CHO-K1 β-Arrestin Orphan GPCR Assay Kit N/A

    GPR143 involved in several pathways and played different roles in them. We selected most pathways GPR143 participated on our site, such as GPCRs, Other, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR143 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCRs, Other EMR2; VN1R1; LGR6; VMN1R49; VMN1R47; SSTR2; VMN1R43; VMN1R52; PROKR2; SETD6

    GPR143 has several biochemical functions, for example, G-protein coupled receptor activity, L-DOPA binding, L-DOPA receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR143 itself. We selected most functions GPR143 had, and list some proteins which have the same functions with GPR143. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity OR4D2; LPAR2B; TAS2R103; MRGPRB2; GPR150; GPR183A; PRLHR; OPN5; OR2A42; PTGER1B
    L-DOPA binding GPR143
    L-DOPA receptor activity GPR143
    dopamine binding TH; DRD3; SLC6A3; DRD5; DRD2B; DRD4; DRD2L; GPR143; DRD2; ADRB2
    protein binding ZYX; OAS1; PKM2; NR4A1; CENPL; ATP1B2; HSPA12B; TRPC7; GPRIN2; ATG13
    tyrosine binding ORA1; YARS2; GPR143

    GPR143 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR143 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR143.

    MLANA

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