GPX2 Protein, glutathione peroxidase 2 (gastrointestinal)


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Official Full Name glutathione peroxidase 2 (gastrointestinal)
Background This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
Synonyms GPX2; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase 2; GSHPX GI; Gastrointestinal glutathione peroxidase; GI GPx; Glutathione peroxidase gastrointestinal; Glutathione peroxidase related protein 2; Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP; GPRP-2; GPx 2; GPx-2; GPx-GI; GPX2_HUMAN; GSHPx 2; GSHPx-2; GSHPx-GI; gastrointestinal glutathione peroxidase 2; GI-GPx
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GPX2-1325H Recombinant Human Gutathione Proxidase 2 (gastrointestinal), His-tagged E.coli His
    Human GPX2-29071TH Recombinant Human GPX2, His-tagged E.coli His
    Human GPX2-5309H Recombinant Human GPX2 Protein, His-tagged E.coli His
    Human GPX2-5762HCL Recombinant Human GPX2 293 Cell Lysate HEK293 N/A
    Mouse GPX2-7231M Recombinant Mouse GPX2 Protein Mammalian Cell His
    Chicken GPX2-5203C Recombinant Chicken GPX2 Mammalian Cell His

    GPX2 involved in several pathways and played different roles in them. We selected most pathways GPX2 participated on our site, such as Glutathione metabolism, Arachidonic acid metabolism, Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glutathione metabolism IDH2; GPX4A; GPX4; GSTAL; GPX5; IDH1; GSTT2; GSTM1; GSTP2; GGCT
    Arachidonic acid metabolism ALOX15; DPEP2; CYP2J5; CYP2P7; PLA2G6; PTGDSB; TBXAS1; GGTLC1; CYP2AD3; PLA2G4D
    Thyroid hormone synthesis PLCB1; ATP1B1; SLC26A4; DUOXA2; TPO; GPX2; GNAS; DUOX2; TTF2; SLC5A5

    GPX2 has several biochemical functions, for example, electron carrier activity, glutathione peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPX2 itself. We selected most functions GPX2 had, and list some proteins which have the same functions with GPX2. You can find most of the proteins on our site.

    Function Related Protein
    electron carrier activity GRXCR1; ACAD9; GCDHB; CYBA; COX7A1; PRKRA; ACOX1; GRX2; NCF1; SRD5A1
    glutathione peroxidase activity GPX5; GRX2; GPX7; GSTT1; GSTK1; GSTZ1; GPX3; GPX4B; GPX6; GPX1

    GPX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPX2.

    MYC; TP53; PSMB2

    van den Berg, L; Koelsch, BU; et al. Genetic dissection of the Mss4 locus mediating sex-biased cancer resistance in the rat peripheral nervous system. INTERNATIONAL JOURNAL OF CANCER 136:2099-2108(2015).
    Bajak, E; Fabbri, M; et al. Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles. TOXICOLOGY LETTERS 233:187-199(2015).

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