gpx3
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  • Official Full Name
  • glutathione peroxidase 3 (plasma)
  • Background
  • This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen;peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA;codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop;structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather;than as a stop signal.
  • Synonyms
  • GPX3; glutathione peroxidase 3 (plasma); glutathione peroxidase 3; GPx-3; plasma glutathione peroxidase; extracellular glutathione peroxidase; GPx-P; GSHPx-3; GSHPx-P
Cat.#:GPX3-5310HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GPX3 Protein, His-tagged
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Cat.#:GPX3-1928HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Glutathione Peroxidase 3 (plasma), His-tagged
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Cat.#:GPX3-219HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GPX3
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Cat.#:GPX3-29075THTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human GPX3, FLAG-tagged
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Cat.#:GPX3-29077THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GPX3, His-tagged
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Cat.#:GPX3-8201HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GPX3 protein, His & T7-tagged
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Cat.#:Gpx3-284MTag:Flag
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Gpx3, FLAG-tagged
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Cat.#:Gpx3-625MTag:Flag
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Glutathione Peroxidase 3 (Plasma), FLAG-tagged
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Cat.#:GPX3-7232MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GPX3 Protein
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Cat.#:Gpx3-8202MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gpx3 protein, His & T7-tagged
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Cat.#:GPX3-2678RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GPX3 Protein
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Cat.#:GPX3-3974CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GPX3
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Cat.#:GPX3-7216ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GPX3
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Involved Pathway

GPX3 involved in several pathways and played different roles in them. We selected most pathways GPX3 participated on our site, such as Glutathione metabolism, Arachidonic acid metabolism, Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glutathione metabolism
GGCTA; GSTP2; GGT1; GSTO2; SMS; MGST1; ODC1; GSTT1B; GSTA2; GPX2
Arachidonic acid metabolism
FAAH2; CYP2C54; TBXAS1; PTGDSA; GPX6; GGT1; PLA2G4A; PLB1; CYP1A2; CYP2C45
Thyroid hormone synthesis
PDIA4; ATP1B1; GPX1; PAX8; CREB3L1; ATP1B4; PRKACB; ATP1A2; GPX7; HSP90B1

Protein Function

GPX3 has several biochemical functions, for example, glutathione peroxidase activity, protein binding, selenium binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPX3 itself. We selected most functions GPX3 had, and list some proteins which have the same functions with GPX3. You can find most of the proteins on our site.
Function
Related Protein
Function glutathione peroxidase activity
Related Protein GSTZ1; GPX7; LTC4S; GPX5; GPX4; GPX4A; GPX1B; MGST3; GRX2; PRDX6
Function protein binding
Related Protein ILF3; SYNDIG1; PSMA1; ERP27; CUL1; SKP1; SNAPC5; LSM11; PRKAR1A; RBMX
Function selenium binding
Related Protein GPX3; DIO2; SEP15; SEPP1; SELT; RPH3A; SELENBP2; DIO1; GPX1; SELENBP1
Function transcription factor binding
Related Protein KAT2B; E2F2; PIAS2; PYDC3; NAB2; DAXX; AGTR2; FOXA3; MAFB; HIF1A

Interacting Protein

GPX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPX3.
UBQLN1; q7cgd4_yerpe; ohrA; trmFO; fadH; livM2; ftsY

GPX3 Related Articles

Anugu, S; Petersson-Wolfe, CS; et al. Effect of vitamin E on the immune system of ewes during late pregnancy and lactation. SMALL RUMINANT RESEARCH 111:83-89(2013).
Lee, HJ; Do, JH; et al. Immunohistochemical evidence for the over-expression of Glutathione peroxidase 3 in clear cell type ovarian adenocarcinoma. MEDICAL ONCOLOGY 28:S522-S527(2011).