GPX3

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GPX3

Official Full Name glutathione peroxidase 3 (plasma)
Background This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen;peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA;codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop;structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather;than as a stop signal.
Synonyms GPX3; glutathione peroxidase 3 (plasma); glutathione peroxidase 3; GPx-3; plasma glutathione peroxidase; extracellular glutathione peroxidase; GPx-P; GSHPx-3; GSHPx-P
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • Flag
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GPX3-1928H Recombinant Human Glutathione Peroxidase 3 (plasma), His-tagged His
    Human GPX3-219H Recombinant Human GPX3 Mammalian Cell His
    Human GPX3-29075TH Recombinant Human GPX3, FLAG-tagged HEK293 Flag
    Human GPX3-29077TH Recombinant Human GPX3, His-tagged E.coli His
    Human GPX3-5310H Recombinant Human GPX3 Protein, His-tagged E.coli His
    Human GPX3-8201H Recombinant Human GPX3 protein, His & T7-tagged E.coli His/T7
    Mouse Gpx3-284M Recombinant Mouse Gpx3, FLAG-tagged HEK293 Flag
    Mouse Gpx3-625M Recombinant Mouse Glutathione Peroxidase 3 (Plasma), FLAG-tagged HEK293 Flag
    Mouse GPX3-7232M Recombinant Mouse GPX3 Protein Mammalian Cell His
    Mouse Gpx3-8202M Recombinant Mouse Gpx3 protein, His & T7-tagged E.coli His/T7
    Rat GPX3-2678R Recombinant Rat GPX3 Protein Mammalian Cell His
    Chicken GPX3-3974C Recombinant Chicken GPX3 Mammalian Cell His
    Zebrafish GPX3-7216Z Recombinant Zebrafish GPX3 Mammalian Cell His

    GPX3 involved in several pathways and played different roles in them. We selected most pathways GPX3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glutathione metabolism SMS; GPX4; GGT1A; GGCTB; GSTM5; GSTM; TXNDC12; GSTK1; IDH2; GSTA
    Arachidonic acid metabolism HPGDS; PLA2G4AA; CYP4F11; PTGS2; CYP2J5; PLA2G2D; ALOX5; CYP2P8; PLA2G4C; CYP2C45
    Thyroid hormone synthesis GPX8; ASGR1; ATP1A1; ATP1B2; Adcy4; ASGR2; PLCB1; GPX2; ITPR1; PRKCB

    GPX3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GPX3 itself. We selected most functions GPX3 had, and list some proteins which have the same functions with GPX3. You can find most of the proteins on our site.

    Function Related Protein
    glutathione peroxidase activity GPX4; GPX8; MGST3; CLIC2; GPX1; GPX4A; GPX3; GPX4B; GPX1B; GSTZ1
    protein binding INTS9; KCNH1; LIMD1; JUB; LIMK1; SRM; GALNT2; CXCR5; TTC6; PLAA
    selenium binding SELENBP2; DIO1; SEP15; SEPP1; SELENBP1; GPX3; RPH3A; GPX1; SELT; DIO2
    transcription factor binding NAB2; FOXA1; ZBTB49; NLK; STK4; E2F1; NEUROD1; ATF7; NKX2-5; EPN1

    GPX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPX3.

    UBQLN1; q7cgd4_yerpe; ohrA; trmFO; fadH; livM2; ftsY

    Anugu, S; Petersson-Wolfe, CS; et al. Effect of vitamin E on the immune system of ewes during late pregnancy and lactation. SMALL RUMINANT RESEARCH 111:83-89(2013).
    Lee, HJ; Do, JH; et al. Immunohistochemical evidence for the over-expression of Glutathione peroxidase 3 in clear cell type ovarian adenocarcinoma. MEDICAL ONCOLOGY 28:S522-S527(2011).

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