Recombinant Human GPX3, FLAG-tagged

• Cat.No.: GPX3-29075TH
• Product Overview: Recombinant full length Human Glutathione Peroxidase 3 with an N terminal DDDDK tag; MWt 30 kDa .

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 206 amino acids
• Description: This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
• Conjugation: FLAG
• Molecular Weight: 30.000kDa inclusive of tags
• Tissue specificity: Secreted in plasma.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS, pH 7.2
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the glutathione peroxidase family.

Gene Information

• Gene Name: GPX3 glutathione peroxidase 3 (plasma) [ Homo sapiens ]
• Official Symbol: GPX3
• Synonyms: GPX3; glutathione peroxidase 3 (plasma); glutathione peroxidase 3
• Gene ID: 2878
• mRNA Refseq: NM_002084
• Protein Refseq: NP_002075
• MIM: 138321
• Uniprot ID: P22352
• Chromosome Location: 5q23
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem
• Function: glutathione binding; glutathione peroxidase activity; glutathione peroxidase activity; oxidoreductase activity; selenium binding