|Official Full Name||general transcription factor IIH, polypeptide 4, 52kDa|
|Background||General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.|
|Synonyms||GTF2H4; general transcription factor IIH, polypeptide 4, 52kDa; general transcription factor IIH, polypeptide 4 (52kD subunit); general transcription factor IIH subunit 4; TFB2; TFIIH; Basic transcription factor 2 52 kDa subunit; Basic transcription factor 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4 52kDa; General transcription factor IIH polypeptide 4 52kDa subunit; General transcription factor IIH polypeptide 4 52kDa variant; General transcription factor IIH polypeptide 4; OTTHUMP00000029049; OTTHUMP00000164874; TF2H4_HUMAN; TFIIH basal transcription factor complex p52 subunit; TFIIH protein; TIFIIH; Transcription factor II H; Transcription factor IIH 52 kDa subunit|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GTF2H4 involved in several pathways and played different roles in them. We selected most pathways GTF2H4 participated on our site, such as Basal transcription factors, Nucleotide excision repair, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Basal transcription factors||TAF8; GTF2A1L; GTF2F2A; MNAT1; GTF2H3-2; TAF3; TBPL1; GTF2H2C; TAF7L; TAF11|
|Nucleotide excision repair||POLD4; GTF2H4; GTF2H3-2; PPIE; KIAA1530; RFC3; COPS7A; POLD2; YY1; RPA1|
|Viral carcinogenesis||TRP53; RBPJL; HLA-G; MDM2; LTBR; H2BFWT; RANBP1; IRF3; KAT2B; TBPL1|
GTF2H4 has several biochemical functions, for example, ATP-dependent DNA helicase activity, contributes_to DNA-dependent ATPase activity, contributes_to RNA polymerase II carboxy-terminal domain kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H4 itself. We selected most functions GTF2H4 had, and list some proteins which have the same functions with GTF2H4. You can find most of the proteins on our site.
|ATP-dependent DNA helicase activity||BRIP1; DHX9; G3BP1; CHD1; CHD2; WRN; XRCC6; BLM; FBXO18; RECQL|
|contributes_to DNA-dependent ATPase activity||MNAT1; RBBP4; ERCC2; GTF2H2; GTF2H1; GTF2H4; GTF2H3; BPTF; ERCC3|
|contributes_to RNA polymerase II carboxy-terminal domain kinase activity||GTF2H2; ERCC3; GTF2H1; MNAT1; GTF2H4; ERCC2; GTF2H3|
|double-stranded DNA binding||TP73; USF1; XRCC2; HNRNPDL; CTNNB1; DDX11; AKAP8; HMGB2; AFF3; RAD51|
|protein binding||GCKR; PLEKHN1; AGFG1; SCMH1; BRPF3; ASB2; F2RL1; HEATR5B; CCDC120; PPFIA2|
|contributes_to protein kinase activity||GTF2H3; GTF2H2; GTF2H4; ERCC3; GTF2H1; ERCC2|
|transcription factor activity, sequence-specific DNA binding||ZNF83; ZNF583; SPZ1; FLI1; ZNF624; NCOR1; ZNF498; RXRGB; SIX4; HOXB6A|
GTF2H4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H4.
CDK7; Rpl35; GTF2H5