GTF2H4 Protein, general transcription factor IIH, polypeptide 4, 52kDa


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Official Full Name general transcription factor IIH, polypeptide 4, 52kDa
Background General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.
Synonyms GTF2H4; general transcription factor IIH, polypeptide 4, 52kDa; general transcription factor IIH, polypeptide 4 (52kD subunit); general transcription factor IIH subunit 4; TFB2; TFIIH; Basic transcription factor 2 52 kDa subunit; Basic transcription factor 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4 52kDa; General transcription factor IIH polypeptide 4 52kDa subunit; General transcription factor IIH polypeptide 4 52kDa variant; General transcription factor IIH polypeptide 4; OTTHUMP00000029049; OTTHUMP00000164874; TF2H4_HUMAN; TFIIH basal transcription factor complex p52 subunit; TFIIH protein; TIFIIH; Transcription factor II H; Transcription factor IIH 52 kDa subunit
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GTF2H4-28282TH Recombinant Human GTF2H4 Wheat Germ N/A
    Human GTF2H4-421H Recombinant Human GTF2H4 Protein, His-tagged E.coli His
    Human GTF2H4-4452H Recombinant Human GTF2H4 Protein, GST-tagged Wheat Germ GST
    Human GTF2H4-5694HCL Recombinant Human GTF2H4 293 Cell Lysate HEK293 N/A
    Mouse GTF2H4-7361M Recombinant Mouse GTF2H4 Protein Mammalian Cell His
    Rhesus Macaque GTF2H4-2008R Recombinant Rhesus monkey GTF2H4 Protein, His-tagged Mammalian Cell His
    Chicken GTF2H4-2028C Recombinant Chicken GTF2H4 Mammalian Cell His
    Zebrafish GTF2H4-10294Z Recombinant Zebrafish GTF2H4 Mammalian Cell His

    GTF2H4 involved in several pathways and played different roles in them. We selected most pathways GTF2H4 participated on our site, such as Basal transcription factors, Nucleotide excision repair, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basal transcription factors TAF8; GTF2A1L; GTF2F2A; MNAT1; GTF2H3-2; TAF3; TBPL1; GTF2H2C; TAF7L; TAF11
    Nucleotide excision repair POLD4; GTF2H4; GTF2H3-2; PPIE; KIAA1530; RFC3; COPS7A; POLD2; YY1; RPA1
    Viral carcinogenesis TRP53; RBPJL; HLA-G; MDM2; LTBR; H2BFWT; RANBP1; IRF3; KAT2B; TBPL1

    GTF2H4 has several biochemical functions, for example, ATP-dependent DNA helicase activity, contributes_to DNA-dependent ATPase activity, contributes_to RNA polymerase II carboxy-terminal domain kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H4 itself. We selected most functions GTF2H4 had, and list some proteins which have the same functions with GTF2H4. You can find most of the proteins on our site.

    Function Related Protein
    ATP-dependent DNA helicase activity BRIP1; DHX9; G3BP1; CHD1; CHD2; WRN; XRCC6; BLM; FBXO18; RECQL
    contributes_to DNA-dependent ATPase activity MNAT1; RBBP4; ERCC2; GTF2H2; GTF2H1; GTF2H4; GTF2H3; BPTF; ERCC3
    contributes_to RNA polymerase II carboxy-terminal domain kinase activity GTF2H2; ERCC3; GTF2H1; MNAT1; GTF2H4; ERCC2; GTF2H3
    double-stranded DNA binding TP73; USF1; XRCC2; HNRNPDL; CTNNB1; DDX11; AKAP8; HMGB2; AFF3; RAD51
    protein binding GCKR; PLEKHN1; AGFG1; SCMH1; BRPF3; ASB2; F2RL1; HEATR5B; CCDC120; PPFIA2
    contributes_to protein kinase activity GTF2H3; GTF2H2; GTF2H4; ERCC3; GTF2H1; ERCC2
    transcription factor activity, sequence-specific DNA binding ZNF83; ZNF583; SPZ1; FLI1; ZNF624; NCOR1; ZNF498; RXRGB; SIX4; HOXB6A

    GTF2H4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H4.

    CDK7; Rpl35; GTF2H5

    Kim, JY; Kim, JH; et al. Lack of association between GTF2H4 genetic variants and AERD development and FEV1 decline by aspirin provocation. INTERNATIONAL JOURNAL OF IMMUNOGENETICS 39:486-491(2012).
    Buch, SC; Diergaarde, B; et al. Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer. MOLECULAR CARCINOGENESIS 51:E11-E20(2012).

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