• Official Full Name
  • glycophorin C (Gerbich blood group)
  • Background
  • Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due todeletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B.
  • Synonyms
  • GYPC; glycophorin C (Gerbich blood group); glycophorin-C; CD236; CD236R; Ge; GPC; GYPD; GLPC; GLPC_HUMAN; Glycoconnectin; Glycophorin D; Glycophorin-D; Glycoprotein beta; GPD; MGC117309; MGC126191; MGC126192; PAS 2; PAS-2; Sialoglycoprotein D; OTTHUMP00000162176; OTTHUMP00000203779
Source (Host):HEK293Species:Human
Product nameRecombinant Human GYPC Protein, MYC/DDK-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GYPC Protein
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GYPC Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GYPC, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GYPC protein, His & GST-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human GYPC Protein, His-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gypc protein, His & GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GYPC Protein
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gypc protein, His & GST-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GYPC Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GYPC
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GYPC
Source (Host):Species:Human
Product nameRecombinant Human GYPC cell lysate

Involved Pathway

GYPC involved in several pathways and played different roles in them. We selected most pathways GYPC participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with GYPC were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
CD40; VCAM1; IL6; ITGB2L; SDC2; MYD88; TLR9; CD36; KLRB1; IL12A

Protein Function

GYPC has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GYPC itself. We selected most functions GYPC had, and list some proteins which have the same functions with GYPC. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein ZNF567; H2AFZ; JPH2; PAGE1; LYL1; RPN1; IFNA2; FAIM; TRIM44; MEMO1

Interacting Protein

GYPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GYPC here. Most of them are supplied by our site. Hope this information will be useful for your research of GYPC.

GYPC Related Articles

Guzvic, M; Braun, B; et al. Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes. CANCER RESEARCH 74:7383-7394(2014).
Uchikawa, M; Tsuneyama, H; et al. A new high-molecular-weight glycophorin C variant with a duplication of exon 2 in the glycophorin C gene. TRANSFUSION MEDICINE 7:305-309(1997).