|Official Full Name||histocompatibility 2, D region locus 1|
|Background||The "classical" MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.|
|Synonyms||H2-D1; histocompatibility 2, D region locus 1; H-2 class I histocompatibility antigen, L-D alpha chain; Q5k protein; MHC class I H-2Dp; MHC H2-D-q alpha-chain; MHC class I H2 antigen; H-2D cell surface glycoprotein; H2-DC1-beta transplantation antigen pro|
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H2-D1 involved in several pathways and played different roles in them. We selected most pathways H2-D1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
H2-D1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by H2-D1 itself. We selected most functions H2-D1 had, and list some proteins which have the same functions with H2-D1. You can find most of the proteins on our site.
H2-D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-D1.