H2AFX Protein, H2A histone family, member X

H2AFX

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H2AFX

Official Full Name H2A histone family, member X
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008]
Synonyms H2AFX; H2A histone family, member X; H2AX; H2A.X; H2A/X; histone H2AX; H2AX histone; histone H2A.x;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human H2AFX-124H Recombinant Human H2AFX protein E.coli N/A
    Human H2AFX-13646H Recombinant Human H2AFX, GST-tagged E.coli GST
    Human H2AFX-1513H Recombinant Human H2AFX protein, His & GST-tagged E.coli His/GST
    Human H2AFX-2059H Recombinant Human H2A Histone Family, Member X E.coli N/A
    Human H2AFX-5659HCL Recombinant Human H2AFX 293 Cell Lysate HEK293 N/A
    Human H2AFX-68H Recombinant Human H2AFX protein, GST-tagged Wheat Germ GST
    Mouse H2AFX-7429M Recombinant Mouse H2AFX Protein Mammalian Cell His
    Rhesus Macaque H2AFX-2027R Recombinant Rhesus monkey H2AFX Protein, His-tagged Mammalian Cell His
    Zebrafish H2AFX-11299Z Recombinant Zebrafish H2AFX Mammalian Cell His

    H2AFX involved in several pathways and played different roles in them. We selected most pathways H2AFX participated on our site, such as Alcoholism, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2AFX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alcoholism HIST1H3D; CALM1; GNAS; HIST1H2AE; HIST1H2BG; HDAC8; GNGT2; HIST4H4; HIST1H4A; HIST1H4N
    Systemic lupus erythematosus HIST1H4L; HIST1H3F; HIST1H4D; C7; C1S; H3F3A; HIST1H2AH; HIST2H2AA4; HIST1H2BL; HIST1H2BE

    H2AFX has several biochemical functions, for example, DNA binding, damaged DNA binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by H2AFX itself. We selected most functions H2AFX had, and list some proteins which have the same functions with H2AFX. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZNF292A; IRF1; H1M; FOXN4; RAD51L1; FOSB; NHEJ1; ZNF280D; NTNG1; ZNF7
    damaged DNA binding GTF2H3; TRPC2; POLH; TDG; CRY-DASH; POLD1; RPS3; HMGB1; POLK; RAD52
    enzyme binding RPS19BP1; C6orf211; UBE2L3; CABYR; HINFP; TTN; GBP1; LAMB1; CCND1; TMBIM6
    histone binding HIST1H3A; ANP32B; PRMT6; HIST1H4H; DAXX; L3MBTL2; PHF21B; CTSL1; HIST1H3F; BRD1
    protein binding HNF4A; BCKDHA; CIAPIN1; NAT8B; HER5; DPF2; MZF1; NUS1; COL10A1; USP54
    protein heterodimerization activity DMRT3A; F11R.1; HGF; H2AFB3; EXT1; SMAD1; HER5; PANX1; HIST1H2AL; H2AFZ

    H2AFX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2AFX here. Most of them are supplied by our site. Hope this information will be useful for your research of H2AFX.

    MDC1; NBN

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