Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

HAND2

  • Official Full Name

    heart and neural crest derivatives expressed 2

  • Overview

    The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
  • Synonyms

    HAND2; heart and neural crest derivatives expressed 2; heart- and neural crest derivatives-expressed protein 2; bHLHa26; dHand; Hed; Thing2; class A basic helix-loop-helix protein 26; basic helix-loop-helix transcription factor HAND2; deciduum, heart, aut;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HAND2-4568H Recombinant Human HAND2 Protein, GST-tagged Wheat Germ GST
Human HAND2-13663H Recombinant Human HAND2, GST-tagged E.coli GST 1-26+33-77a.a.
Human HAND2-3350HF Recombinant Full Length Human HAND2 Protein, GST-tagged In Vitro Cell Free System GST 180 amino acids
Human HAND2-3015H Recombinant Human HAND2 protein, GST-tagged E.coli GST 1-180aa
Mouse HAND2-7474M Recombinant Mouse HAND2 Protein Mammalian Cell His
Mouse HAND2-4054M-B Recombinant Mouse HAND2 Protein Pre-coupled Magnetic Beads HEK293
Mouse HAND2-4054M Recombinant Mouse HAND2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HAND2-2787R Recombinant Rat HAND2 Protein Mammalian Cell His
Rat HAND2-2441R-B Recombinant Rat HAND2 Protein Pre-coupled Magnetic Beads HEK293
Rat HAND2-2441R Recombinant Rat HAND2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HAND2-2034R Recombinant Rhesus monkey HAND2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HAND2-1855R Recombinant Rhesus Macaque HAND2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HAND2-1855R-B Recombinant Rhesus Macaque HAND2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HAND2-9164Z Recombinant Zebrafish HAND2 Mammalian Cell His
Chicken HAND2-6525C Recombinant Chicken HAND2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HAND2 involved in several pathways and played different roles in them. We selected most pathways HAND2 participated on our site, such as Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, Neuronal System, Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAND2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutamate Binding, Activation of AMPA Receptors and Synaptic PlasticityPICK1;MYO6;NSFB;NSFA;AKAP5;CACNG3;CACNG2;HAND2;GRIP1
Neuronal SystemRERG;KCNK3A;KCNAB2B;PPFIA2;KCNK16;KCNC4;HCN4;KCNG3;KCNC1B
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellCAMKK1B;MYO6;CHRNE;GRIP1;DLG1L;NSFB;CHRNA5;PICK1;CHRNA2
Trafficking of AMPA receptorsHAND2;GRIP1;PICK1
Trafficking of GluR2-containing AMPA receptorsHAND2;PICK1;GRIP1
Transmission across Chemical SynapsesSLC6A1A;CACNG2B;SYT1A;SLC18A3A;BZRAP1;SLC1A3B;SLC1A2A;PPFIA2;CAMKK1B

HAND2 has several biochemical functions, for example, ATPase activity, Arp2/3 complex binding, G-protein coupled receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HAND2 itself. We selected most functions HAND2 had, and list some proteins which have the same functions with HAND2. You can find most of the proteins on our site.

Function Related Protein
ATPase activityATAD2B;KIF27;ENTPD2;DYNC1H1;HSPA8;ATAD1A;ABCG2D;PSMD6;Abca2
Arp2/3 complex bindingCORO1B;WHAMM;HAND2;GMFB;SNX9;PICK1;ARPC2;GMFG
G-protein coupled receptor bindingNMS;QRFP;GNA12A;CORT;GNA14;RSPO2;PSAPL1;GNA13A;PROK2
actin filament bindingGAS2L2;DBNLB;FSCN1A;CORO2B;TMOD1;MICALL2;SHROOM4;EZR;CTNNA1
enzyme bindingPHB;CLSTN2;CYP2A6;TH;TSPAN14;LYN;HDAC2;KPNB1;MAT2B
identical protein bindingSYT9;MYD88;CD247;TYROBP;TRIM55;THG1L;CLDN7;SMAD3;ATL2
metal ion bindingTRIM35-28;RFWD2;TCN2;FEZF1;AMDHD2;PARP12;ADIPOR1;CTCFL;RNFT1
protein C-terminus bindingNCF2;XRCC5;MKI67;VTA1;VGLL1;AXIN1;RABAC1;PIAS3;PDZD11
protein bindingE2F8;TFAM;SOCS1;RBM25;PRKRIP1;CYTIP;LCE4A;JAKMIP1;GRIA2
protein domain specific bindingDDX6;PLG;HOMER2;TJP2;RARA;AKAP5;MECP2;Akap2;GNAI3
protein kinase C bindingFEZ1;DACT1;DACT3;GNB2L1;TDG;PAWR;PARD3;TOP2B;SDPRA
receptor bindingAKAP9;F2;CRTAM;FYB;CD58;HSPA1A;SLC9A3R1;NRXN1;WIPI1

HAND2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAND2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAND2.

TCF4

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All HAND2 Products

Required fields are marked with *

My Review for All HAND2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends