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HIP1R

  • Official Full Name

    huntingtin interacting protein 1 related

  • Overview

    Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
  • Synonyms

    HIP1R; huntingtin interacting protein 1 related; HIP3; HIP12; ILWEQ; huntingtin-interacting protein 1-related protein; HIP-12; HIP1-related protein; huntingtin interacting protein 12; huntingtin-interacting protein 12;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HIP1R-13784H Recombinant Human HIP1R, GST-tagged E.coli GST 266-615a.a.
Human HIP1R-30H Recombinant Human HIP1R, MYC/DDK-tagged HEK293 Myc/DDK
Human HIP1R-29320TH Recombinant Human HIP1R, His-tagged E.coli His
Human HIP1R-7857H Recombinant Human HIP1R protein, His & T7-tagged E.coli His/T7 Ser771~Ala1012 (Accession # O75146)
Human HIP1R-29H Recombinant Human HIP1R, GST-tagged Wheat Germ GST
Human HIP1R-789HCL Recombinant Human HIP1R cell lysate N/A
Human HIP1R-4385H Recombinant Human HIP1R Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HIP1R-9016HFL Recombinant Full Length Human HIP1R, Flag-tagged Mamanlian cells Flag
Human HIP1R-3232H Recombinant Human HIP1R Protein (Ser771-Ala1012), N-His tagged E.coli N-His Ser771-Ala1012
Human HIP1R-560HF Recombinant Full Length Human HIP1R Protein, GST-tagged In Vitro Cell Free System GST 1068 amino acids
Mouse HIP1R-7635M Recombinant Mouse HIP1R Protein Mammalian Cell His
Mouse HIP1R-4168M-B Recombinant Mouse HIP1R Protein Pre-coupled Magnetic Beads HEK293
Mouse HIP1R-4168M Recombinant Mouse HIP1R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hip1r-3399M Recombinant Mouse Hip1r Protein, Myc/DDK-tagged HEK293T Myc/DDK
Chicken HIP1R-2363C Recombinant Chicken HIP1R Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HIP1R involved in several pathways and played different roles in them. We selected most pathways HIP1R participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIP1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Clathrin derived vesicle buddingNAPAB;SNX9A;TPD52L1;TBC1D8B;BLOC1S4;NAPAA;AP1B1;AP3S1;SNX9
Golgi Associated Vesicle BiogenesisFTH1A;FTH1B;PLDN;AP4B1;TPD52;DTNBP1B;HIP1RB;AP1G1;CLINT1
Membrane TraffickingAP3S1;MIA3;AP4B1;SH3D19;SNF8;EXOC5;PPP6C;PPP6R3;TPD52
Vesicle-mediated transportMYO6A;AP4B1;MIA3;CPD;SEC22A;TGOLN2;TRAPPC1;GJB5;NAPB
trans-Golgi Network Vesicle BuddingTCEAL4;CLVS1;SH3D19;PICALMB;PLDN;DNASE2;HIP1RB;AP3S1;DTNBP1

HIP1R has several biochemical functions, for example, actin binding, clathrin binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIP1R itself. We selected most functions HIP1R had, and list some proteins which have the same functions with HIP1R. You can find most of the proteins on our site.

Function Related Protein
actin bindingSNTB2;PHACTR1;LSP1;FHOD3;SPTB;PHACTR3A;VASPA;ACTR2A;FLII
clathrin bindingAFTPHA;SYT1B;AP2B1;DNER;DOC2D;TOM1;SYT12;HIP1;LRRK2
phosphatidylinositol bindingPASK;SNX32;RPS6KC1;SNX27;TUB;SNX15;SNX27B;SNX4;PLD1A
protein bindingUBAC1;TTF2;FEM1C;ISY1;GAST;MED9;SNAP47;EIF3D;FBL

HIP1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIP1R here. Most of them are supplied by our site. Hope this information will be useful for your research of HIP1R.

q53hg7_human; UBA1; UBE2N; UBE2V1; Map3k1; pi3p; Sec24c; GAK; CLTB; VCAM1; MYH9; CAPZA2; CD81; Actb

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