HK1
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Official Full Name
Hexokinase 1
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Overview
Hexokinase-1 is an enzyme that in humans is encoded by the HK1 gene. -
Synonyms
HK1; Hexokinase 1; HK1-ta; HK1-tb; HK1-tc; HKI; HXK1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- His|GST
- His|Twin Strep
- SUMO
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- HK1 Related Articles
- HK1 Related Research Area
HK1 involved in several pathways and played different roles in them. We selected most pathways HK1 participated on our site, such as Glycolysis / Gluconeogenesis, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Glycolysis / Gluconeogenesis | LDHC;MINPP1A;HK2;ENO1B;GALM;GM5506;ALDH3B2;ALDH9A1;ALDH9A1A.1 |
Fructose and mannose metabolism | C12orf5;GMDS;PFKP;PFKMB;HK1;ALDOAB;TPI1A;ALDOCA;KHK |
Galactose metabolism | HK2;AKR1B1L;B4GALT1;B4GALT2;PFKP;GAA;PFKL;UGP2A;PGM1 |
Starch and sucrose metabolism | UGT1A9;GPIB;ENPP3;UGT2A1;PYGMA;GBA3;UXS1;PGM1;PYGB |
Amino sugar and nucleotide sugar metabolism | PMM2;GPI1;CYB5R3;HKDC1;MPI;PMM1;HEXA;PGM1;UGP2A |
Butirosin and neomycin biosynthesis | HK1;HK3;HK2;HKDC1 |
Metabolic pathways | ACLY;SQLE;EARS2;MAN1A2;POLR2B;NT5C1BA;NMNAT2;IVD;ALG1 |
Carbon metabolism | PFKM;FBP2;CPS1;MDH1AA;ALDOAA;RPE;HK1;GLUD1B;IDH3A |
HIF- signaling pathway | PDHA1;IGF1;PIK3CG;MAP2K2;NOX1;HIF1A;PLCG1;MKNK1;PLCG2 |
Insulin signaling pathway | SOCS3B;FOXO1B;MKNK2;SOCS1;MAP2K2A;SOCS9;HRASB;PRKAR1A;CALM1B |
Type II diabetes mellitus | PIK3R1;PIK3CG;PRKCD;SOCS1;MAPK10;INS1;PIK3CA;IRS2;INS-IGF2 |
Carbohydrate digestion and absorption | FXYD2;ATP1B2;ATP1A2;HK1;AKT1;ATP1B1;PIK3CB;PIK3R1;ATP1B3 |
Central carbon metabolism in cancer | HRAS;IDH1;PDHA1;ERBB2;HK2;PIK3R3;SLC1A5;NTRK3;FGFR2 |
HK1 has several biochemical functions, for example, ATP binding, fructokinase activity, glucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HK1 itself. We selected most functions HK1 had, and list some proteins which have the same functions with HK1. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | DDX20;AK2;CLK2;MCM7;PAPD4;MAPK12A;Ckmm;MYHZ1.1;MTPAP |
fructokinase activity | HK1;HKDC1;HK3;HK2 |
glucokinase activity | HKDC1;HK1;HK3;HK2 |
glucose binding | G6PD;G6PDX;HK2;HK1;UGP2;GYS1;HKDC1;HK3;SLC2A3 |
hexokinase activity | HK1;HK3;HK2 |
mannokinase activity | HK3;HK1;HKDC1;HK2 |
protein binding | MLLT10;PTPN7;MAP3K1;WWP2;AGBL1;NFE2L3;TPM1;EPM2AIP1;SEC61G |
HK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HK1.
ATF2; GBAS; VDAC1; MAX; ATG101; ENO2; SCMH1; MYC; ICT1; LRRK2
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