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HOXD8

  • Official Full Name

    homeobox D8

  • Overview

    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5 end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.
  • Synonyms

    HOXD8; homeobox D8; homeo box D8 , HOX4, HOX4E; homeobox protein Hox-D8; Homeobox protein Hox-4E; Homeobox protein Hox-5.4; Hox-4.5; Hox-4E; Hox-5.4; HOX4; HXD8_HUMAN; homeo box 4E; homeo box D8; OTTHUMP00000163337; OTTHUMP00000205236; OTTHUMP00000205237; homeobox protein 5.4; HOX4E; HOX5.4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HOXD8-26896TH Recombinant Human HOXD8 Wheat Germ N/A 65 amino acids
Human HOXD8-13915H Recombinant Human HOXD8, His-tagged E.coli His 1-289a.a.
Human HOXD8-4999H Recombinant Human HOXD8 Protein, GST-tagged Wheat Germ GST
Human HOXD8-5410HCL Recombinant Human HOXD8 293 Cell Lysate HEK293 N/A
Human HOXD8-3737HF Recombinant Full Length Human HOXD8 Protein, GST-tagged In Vitro Cell Free System GST 289 amino acids
Mouse HOXD8-7820M Recombinant Mouse HOXD8 Protein Mammalian Cell His
Mouse HOXD8-4300M-B Recombinant Mouse HOXD8 Protein Pre-coupled Magnetic Beads HEK293
Mouse HOXD8-4300M Recombinant Mouse HOXD8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken HOXD8-7117C Recombinant Chicken HOXD8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HOXD8 involved in several pathways and played different roles in them. We selected most pathways HOXD8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HOXD8 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXD8 itself. We selected most functions HOXD8 had, and list some proteins which have the same functions with HOXD8. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II regulatory region sequence-specific DNA bindingGATA4;ALX4;IKZF3;ZBTB11;ALX1;BARHL2;ZFY1;ATF2;ELF5
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingMAFGA;RAD21;NR1I2;ALX1;LMO2;REST;SRF;GATA5;CREB3L3

HOXD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXD8.

PFDN1; RCC1; ANXA7; CDKN1A; q9wmx2-pro_0000037541; q9wmx2-pro_0000037545; q9wmx2-pro_0000037547; q9wmx2-pro_0000037549; q9wmx2-pro_0000037552

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