HS3ST1 Protein, heparan sulfate (glucosamine) 3-O-sulfotransferase 1


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Official Full Name heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Background Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein.
Synonyms HS3ST1; heparan sulfate (glucosamine) 3-O-sulfotransferase 1; heparan sulfate glucosamine 3-O-sulfotransferase 1; 3OST1; 3-OST-1; 3OST; EC; h3 OST 1; h3-OST-1; Heparan sulfate (glucosamine) 3 O sulfotransferase 1; Heparan sulfate 3 O sulfotransferase 1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 1; Heparin glucosamine 3 O sulfotransferase; HS3ST 1; heparan sulfate 3-O-sulfotransferase 1; heparin-glucosamine 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Hs3st1-1173M Recombinant Mouse Hs3st1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human HS3ST1-1970H Recombinant Human Heparan Sulfate (glucosamine) 3-O-Sulfotransferase 1, His-tagged CHO His
    Human HS3ST1-2320H Recombinant Human HS3ST1, His-tagged E.coli His
    Human HS3ST1-429H Recombinant Human HS3ST1 Protein, His-tagged Insect Cell His
    Human HS3ST1-5049H Recombinant Human HS3ST1 Protein, GST-tagged Wheat Germ GST
    Human HS3ST1-5387HCL Recombinant Human HS3ST1 293 Cell Lysate HEK293 N/A
    Human HS3ST1-926H Recombinant Human HS3ST1 Protein, His-tagged CHO His
    Mouse HS3ST1-7856M Recombinant Mouse HS3ST1 Protein Mammalian Cell His
    Rat HS3ST1-2916R Recombinant Rat HS3ST1 Protein Mammalian Cell His
    Rhesus Macaque HS3ST1-2146R Recombinant Rhesus monkey HS3ST1 Protein, His-tagged Mammalian Cell His
    Zebrafish HS3ST1-5089Z Recombinant Zebrafish HS3ST1 Mammalian Cell His

    HS3ST1 involved in several pathways and played different roles in them. We selected most pathways HS3ST1 participated on our site, such as Glycosaminoglycan biosynthesis - heparan sulfate / heparin, which may be useful for your reference. Also, other proteins which involved in the same pathway with HS3ST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosaminoglycan biosynthesis - heparan sulfate / heparin EXT2; HS3ST3B1; HS3ST1L1; HS3ST1; HS2ST1; HS6ST1B; EXTL2; HS6ST3B; B4GALT7; B3GALT6

    HS3ST1 has several biochemical functions, for example, [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity, sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HS3ST1 itself. We selected most functions HS3ST1 had, and list some proteins which have the same functions with HS3ST1. You can find most of the proteins on our site.

    Function Related Protein
    [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity HS3ST5; HS3ST3B1; HS3ST1; HS3ST4; HS3ST6
    sulfotransferase activity HS3ST3L; SULT1ST8; CHST2A; SULT1A2; SULT2ST3; Chst5; WSCD1; CHST10; HS6ST1B; UST

    HS3ST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HS3ST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HS3ST1.

    Liu, JA; Shriver, Z; et al. Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3A sulfates N-unsubstituted glucosamine residues. JOURNAL OF BIOLOGICAL CHEMISTRY 274:38155-38162(1999).

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