| Official Full Name | heat shock 70kDa protein 9 (mortalin) |
| Background | This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2. |
| Synonyms | HSPA9; heat shock 70kDa protein 9 (mortalin)provided by HGNC; CSA; MOT; MOT2; GRP75; PBP74; GRP-75; HSPA9B; MGC4500; MTHSP75; stress-70 protein, mitochondrial; heat shock 70kDa protein 9 (mortalin) |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
HSPA9 involved in several pathways and played different roles in them. We selected most pathways HSPA9 participated on our site, such as RNA degradation, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPA9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | LSM6; CNOT4; PABPC1A; DCPS; PABPC1L2A; NUDT16; PAPD7; PFKM; PABPC5; CNOT1 |
| Tuberculosis | TNFRSF1A; CD14; IFNGR1; IFNB1; RAB5B; TNF; FADD; IFNA16; STAT1; HLA-DRB1 |
HSPA9 has several biochemical functions, for example, ATP binding, fibroblast growth factor binding, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPA9 itself. We selected most functions HSPA9 had, and list some proteins which have the same functions with HSPA9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | TESK1; SMCHD1; DHX36; MYO6; DDX39B; CAD; TTBK2; NME4; RAD51L3; ABCA13 |
| fibroblast growth factor binding | GLG1; GLG1B; TGFBR3; FIBPB; S100A13; FGFR4; FGFBP3; FGFRL1; GPC1; Api5 |
| heat shock protein binding | DNAJC9; TOMM34; GM5506; HDAC2; PPID; DNAJC7; IRAK1; BCOR; SSUH2.2; DNAJA4 |
| poly(A) RNA binding | ADK; IPO5; UBAP2L; CAST; PRDX1; PUS7; PUF60; NTPCR; MADD; XRCC6 |
| protein binding | PIAS3; SRRT; BCL10; CCDC137; HDHD3; CTNNB2; PSTPIP1; GATA5; RPL27A; CCAR1 |
| ubiquitin protein ligase binding | PA2G4; Fzd4; NKD2; VCP; GPR37; TRAF5; SCAMP3; LRPPRC; SLC25A5; UBE2J2 |
| unfolded protein binding | SCG5; SIL1; HSP90B1; DNAJA3A; CRYABB; AHSP; CALRL2; HSPA1A; APCS; UGGT1 |
HSPA9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPA9 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPA9.
TP53; EGFR; TP73
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