hspd1
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  • Official Full Name
  • heat shock 60kDa protein 1 (chaperonin)
  • Background
  • Heat Shock Protein 60 (HSP60) is a chaperonin with roles in mitochondrial protein import and folding of polypeptides in the mitochondrial matrix.
  • Synonyms
  • HSPD1; heat shock 60kDa protein 1 (chaperonin); heat shock 60kD protein 1 (chaperonin) , spastic paraplegia 13 (autosomal dominant) , SPG13; 60 kDa heat shock protein, mitochondrial; GROEL; HSP60; chaperonin 60; 60 kDa chaperonin; heat shock protein 65
Cat.#:HSPD1-5264HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HSPD1 Protein, GST-tagged
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Cat.#:HSPD1-06HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock 60kDa Protein 1 (Chaperonin)
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Cat.#:HSPD1-326HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock 60kDa Protein 1 (Chaperonin), His-tagged;
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Cat.#:HSPD1-1555HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinent Human HSPD1 protein, His-tagged
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Cat.#:HSPD1-241HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSPD1 protein, His-tagged
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Cat.#:HSPD1-270HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSPD1 protein, His/MBP-tagged
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Cat.#:HSPD1-28422THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSPD1
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Cat.#:HSPD1-29396THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSPD1, His-tagged
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Cat.#:HSPD1-3896HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSPD1, His tagged
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Cat.#:HSPD1-4854HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heat Shock 60kDa Protein 1 (Chaperonin), GST-tagged
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Cat.#:HSPD1-8545HTag:FC/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HSPD1, His-GST tagged
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Cat.#:Hspd1-242MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hspd1 protein, His-tagged
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Cat.#:Hspd1-4058MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hspd1, His tagged
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Cat.#:Hspd1-7778MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hspd1 protein, His & T7-tagged
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Cat.#:HSPD1-7923MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HSPD1 Protein
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Cat.#:Hspd1-243RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Hspd1 protein, His-tagged
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Cat.#:HSPD1-2957RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HSPD1 Protein
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Cat.#:HSPD1-2171RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HSPD1 Protein, His-tagged
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Cat.#:HSPD1-2131CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HSPD1
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Cat.#:HSPD1-9616ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HSPD1
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Cat.#:HSPD1-5340HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HSPD1 293 Cell Lysate
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Cat.#:CSC-P0809Tag:
Source (Host):Species:Human
Product nameAnti-Human HSPD1 MAb Stable Cell Line-CHO
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Cat.#:CSC-P0810Tag:
Source (Host):Species:Human
Product nameAnti-Human HSPD1 F(ab) Stable Cell Line-CHO
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Cat.#:CSC-P0811Tag:
Source (Host):Species:Human
Product nameAnti-Human HSPD1 scFv Stable Cell Line-CHO
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Involved Pathway

HSPD1 involved in several pathways and played different roles in them. We selected most pathways HSPD1 participated on our site, such as RNA degradation, Type I diabetes mellitus, Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RNA degradation
PAN3; PABPC1B; LSM7; CNOT4B; TTC37; SKIV2L; GM5506; LSM8; CNOT6; PNPT1
Type I diabetes mellitus
HLA-DRB4; GAD2; HLA-A; HLA-B; GAD1; INS2; Il2; HLA-DQA1; HLA-DQA2; FAS
Legionellosis
EEF1G; HSPA8; BCL2L13; RAB1B; TNF; CASP1; SEC22B; RELA; CD14; CASP9
Tuberculosis
IL12B; FADD; CALML3; IFNA10; IRAK2; HLA-DPA1; AKT1; FCER1G; PMAP-36; RAF1

Protein Function

HSPD1 has several biochemical functions, for example, ATP binding, ATPase activity, DNA replication origin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPD1 itself. We selected most functions HSPD1 had, and list some proteins which have the same functions with HSPD1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein DNAJA3; MYH11; VARS2; AXL; BMPR2A; PDS5B; BLK; SLC27A5; TOR1B; DHX34
Function ATPase activity
Related Protein HAND2; DYNC2H1; ABCG5; ABCG2B; KIF2C; ABCA4A; OLA1; ABCD3A; HSPA8; ABCC5
Function DNA replication origin binding
Related Protein MCM2; ORC4L; CDC45; ORC3L; HSPD1; MCM10; ORC4; ORC2L; MCM5
Function chaperone binding
Related Protein USP13; ATP1A3; BIRC5; DNAJB4; CTSC; DNAJB2; TIMM10; GET4; TBCE; BAX
Function double-stranded RNA binding
Related Protein OAS1; AGO3; CLTC; HSP90AB1; STRBP; TLR7; SLC3A2; ADARB1; TUBB4B; AGO1
Function insulin binding
Related Protein HSPD1; C2CD2L; IDE; PIK3R1; INSR; IGF1R
Function lipopolysaccharide binding
Related Protein BPIFC; BPI; TLR4; HMGB1; PSMB4; TREM2; CD6; SELP; BPIFA2; LBP
Function misfolded protein binding
Related Protein CLU; HSPA5; F12; STUB1; TOR1A; DNAJC3; DNAJC10; SDF2L1; DNAJB9; HDAC6
Function p53 binding
Related Protein BLM; ANKRD1; BRD4; SETD8; ZNF346; TRP53; CREBBP; EHMT1; RCHY1; MSX1
Function poly(A) RNA binding
Related Protein KIAA1324; FARSA; MAP4; RPF1; PA2G4; RPS19BP1; DDX17; SRSF2; RPL12; ILF2
Function protease binding
Related Protein KIT; TNF; TIMP4; CNTNAP2; ECM1; BDKRB2; CFLAR; LDLR; TNFAIP3; CD70
Function protein binding
Related Protein RBFOX1; TRIM6; AREG; APC; KCNH7; SOAT1; MUS81; RIC8; COG4; NOTCH2NL
Function protein complex binding
Related Protein PPARA; FLCN; BAG3; AP2A1; KAT2B; MLC1; AP2B1; ARRB2; SKAP1; NR0B2
Function protein heterodimerization activity
Related Protein TAF6; HIST2H2AA4; MYF6; STX1A; SDCBP; ADRA2C; BAXB; HIST1H2BN; TLX1; ARNT
Function single-stranded DNA binding
Related Protein LRPPRC; PURB; RAD51; TEN1; PMS1; FUBP1; FBXO18; TTC6; CNBP; CDC45
Function ubiquitin protein ligase binding
Related Protein GRIK2; UBE2O; TRAF3; RAD18; BID; FOXO1; ERBB2; TMEM173; MOAP1; CUL3B
Function unfolded protein binding
Related Protein CALR3; HSPA1A; TAPBP; UGGT1; CHAF1A; HSP104; RUVBL2; HSPA5; CRYABB; AHSP

Interacting Protein

HSPD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPD1.
LZTS2; Smpd3; FHIT; RGS20; RGS20

HSPD1 Related Articles

Kreutmayer, S; Csordas, A; et al. Chlamydia pneumoniae infection acts as an endothelial stressor with the potential to initiate the earliest heat shock protein 60-dependent inflammatory stage of atherosclerosis. CELL STRESS & CHAPERONES 18:259-268(2013).
Hjelholt, A; Carlsen, T; et al. Increased Levels of IgG Antibodies against Human HSP60 in Patients with Spondyloarthritis. PLOS ONE 8:-(2013).