htr2a
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  • Official Full Name
  • 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Background
  • a receptor for 5-hydroxytryptamine (serotonin); activates phospholipase C signaling pathway; involved in promoting cellular transformation
  • Synonyms
  • HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 2A , HTR2; 5-hydroxytryptamine receptor 2A; 5 HT2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor; HTR2; 5-HT2A
Cat.#:HTR2A-1561HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HTR2A, His-tagged
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Cat.#:HTR2A-1729HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HTR2A, His-tagged
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Cat.#:HTR2A-1872HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HTR2A, GST-tagged
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Cat.#:HTR2A-362HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human HTR2A
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Cat.#:HTR2A-7932MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HTR2A Protein
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Cat.#:HTR2A-2962RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HTR2A Protein
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Cat.#:HTR2A-2175RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HTR2A Protein, His-tagged
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Cat.#:Kit-1352Tag:N/A
Source (Host):Species:
Product nameHTR2A U2OS β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0959Tag:N/A
Source (Host):Species:
Product nameTR-FRET VDR Coactivator Assay Kit, goat
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Involved Pathway

HTR2A involved in several pathways and played different roles in them. We selected most pathways HTR2A participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
PRKACBB; TACR2; F2R; AKR1C1; SLC8A3; TNNC1B; AGTR1B; AVPR1A; ADRB3B; RYR1
Neuroactive ligand-receptor interaction
P2RY13; GH2; TAAR14G; SSTR1; TACR2; HTR2C; GABRR3A; NPY8AR; ADRA2DA; GRM2
Gap junction
TUBB; TJP1; DRD2A; HTR2A; GRM5; TUBA8L3; GJD2; HRAS; MAPK7; PDGFRA
Serotonergic synapse
PLA2G4D; PLCB4; NRAS; GNG5; RAF1; PRKCA; CYP2C37; SLC18A1; HTR1F; PRKACA
Inflammatory mediator regulation of TRP channels
PIK3R5; PTGER4; ALOX12; CYP2C37; CALM2; TRPV3; PRKCG; CALM3; TRPV4; PIK3R3

Protein Function

HTR2A has several biochemical functions, for example, 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, G-protein alpha-subunit binding, drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR2A itself. We selected most functions HTR2A had, and list some proteins which have the same functions with HTR2A. You can find most of the proteins on our site.
Function
Related Protein
Function 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
Related Protein HTR2C; HTR2A
Function G-protein alpha-subunit binding
Related Protein OPRM1; F2R; LPAR3; ADRB2; HTR2A; RIC8B; RIC8A; IGF1R; F2RL1; LPAR1
Function drug binding
Related Protein IL2RA; PDE4D; PYGM; MT2A; RARB; CHRNA3; NAMPT; GPR30; FSCN1; CHRNB4
Function protein complex binding
Related Protein LRRC16A; KRT8; DLG4; Ctsl; STRN4; ERCC8; CRIPT; ADM2; EPCAM; WRN
Function serotonin binding
Related Protein HTR2A; HTR2C; HTR1F; HTR1E; HTR3A; MAOA; HTR1B; HTR2B
Function serotonin receptor activity
Related Protein HTR5AL; HTR4; HTR1B; HTR2C; HTR1E; HTR7; HTR2B; HTR2A; HTR3C; HTR1F
Function virus receptor activity
Related Protein SIVA1; PVRL2; TNFRSF14; HSPA1A; CR1; ITGB5; AXL; DPP4; CXADR; ITGAV

Interacting Protein

HTR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR2A.
MPDZ; ketanserin