HTR2A
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Official Full Name
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
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Overview
a receptor for 5-hydroxytryptamine (serotonin); activates phospholipase C signaling pathway; involved in promoting cellular transformation -
Synonyms
HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 2A , HTR2; 5-hydroxytryptamine receptor 2A; 5 HT2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor; HTR2; 5-HT2A;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Bos taurus (Bovine)
- Canis lupus familiaris (Dog) (Canis familiaris)
- Cavia porcellus (Guinea pig)
- Homo sapiens (Human)
- Human
- Macaca mulatta (Rhesus macaque)
- Mouse
- Mus musculus (Mouse)
- Pongo pygmaeus (Bornean orangutan)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Sus scrofa (Pig)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Flag
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- HTR2A Related Research Area
HTR2A involved in several pathways and played different roles in them. We selected most pathways HTR2A participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Calcium signaling pathway | PRKCBB;ATP2A2A;PLCB2;CACNA1D;CAMK2G;OXTR;TRHR;HTR2CL1;NOS1 |
Neuroactive ligand-receptor interaction | TAAR14H;FSHR;BDKRB1;GHRHR;CHRNA5;GRIN1B;HTR5AL;THRA;RXFP2A |
Gap junction | GNA15.1;TUBB5;TUBA4L;GRM5;GNAI1;NRAS;HRAS;TUBA3A;PRKCBB |
Serotonergic synapse | PLCB1;GNG2;CYP2C38;GNGT1;HTR5A;CYP2C50;GNG11;GNB2;BRAF |
Inflammatory mediator regulation of TRP channels | CAMK2A;PLA2G6;TRPA1;CALM1;TRPV3;ASIC1;HTR2C;PRKACA;PTGER2 |
HTR2A has several biochemical functions, for example, 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, G-protein alpha-subunit binding, drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR2A itself. We selected most functions HTR2A had, and list some proteins which have the same functions with HTR2A. You can find most of the proteins on our site.
Function | Related Protein |
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1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding | HTR2A;HTR2C |
G-protein alpha-subunit binding | RIC8B;LPAR3;HTR2B;LPAR1;RIC8;ARHGEF11;RGS19;RIC8A;PPP5C |
drug binding | TOP2A;IL2RA;FOLR2;CYP2C9;CHRNB2;DCK;CHKA;GLRB;CYP4B1 |
protein complex binding | KHDRBS1;TG;CRTAP;PDZK1;RANBP2;RAP1B;ATF1;CYFIP1;ABI2 |
serotonin binding | HTR1B;HTR3A;HTR1F;HTR1E;HTR2C;HTR2A;MAOA;HTR2B |
serotonin receptor activity | HTR1E;HTR3C;HTR3E;HTR1AB;HTR1F;HTR4;HTR3B;HTR5AL;HTR1B |
virus receptor activity | ITGB7;PVR;TYRO3;F11R;HLA-DRB1;AXL;HTR2A;ICAM1;CD80 |
HTR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR2A.
MPDZ; ketanserin
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