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HTR2A

  • Official Full Name

    5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

  • Overview

    a receptor for 5-hydroxytryptamine (serotonin); activates phospholipase C signaling pathway; involved in promoting cellular transformation
  • Synonyms

    HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 2A , HTR2; 5-hydroxytryptamine receptor 2A; 5 HT2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor; HTR2; 5-HT2A;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Cavia porcellus (Guinea pig)
  • Homo sapiens (Human)
  • Human
  • Macaca mulatta (Rhesus macaque)
  • Mouse
  • Mus musculus (Mouse)
  • Pongo pygmaeus (Bornean orangutan)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HTR2A-362H Recombinant Human HTR2A Mammalian Cell His
Human HTR2A-1872H Recombinant Human HTR2A, GST-tagged E.coli GST
Human HTR2A-1561H Recombinant Human HTR2A, His-tagged E.coli His
Human HTR2A-1729H Recombinant Human HTR2A, His-tagged E.coli His
Human HTR2A-3131H Recombinant Human HTR2A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HTR2A-1090HFL Recombinant Human HTR2A protein, His&Flag-tagged HEK293 His&Flag 1-471 aa
Human HTR2A-3131H-B Recombinant Human HTR2A Protein Pre-coupled Magnetic Beads HEK293
Mouse HTR2A-7932M Recombinant Mouse HTR2A Protein Mammalian Cell His
Mouse HTR2A-4374M-B Recombinant Mouse HTR2A Protein Pre-coupled Magnetic Beads HEK293
Mouse HTR2A-4374M Recombinant Mouse HTR2A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HTR2A-2962R Recombinant Rat HTR2A Protein Mammalian Cell His
Rat HTR2A-2617R-B Recombinant Rat HTR2A Protein Pre-coupled Magnetic Beads HEK293
Rat HTR2A-2617R Recombinant Rat HTR2A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL8286BF Recombinant Full Length Bovine 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-470)
Canis lupus familiaris (Dog) (Canis familiaris) RFL22303CF Recombinant Full Length Dog 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-470)
Cavia porcellus (Guinea pig) RFL33008CF Recombinant Full Length Guinea Pig 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-247)
Homo sapiens (Human) RFL5022HF Recombinant Full Length Human 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-471)
Macaca mulatta (Rhesus macaque) RFL20834MF Recombinant Full Length Macaca Mulatta (Rhesus Macaque) 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-471)
Mus musculus (Mouse) RFL31788MF Recombinant Full Length Mouse 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-471)
Pongo pygmaeus (Bornean orangutan) RFL35893PF Recombinant Full Length Pongo Pygmaeus 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-471)
Rattus norvegicus (Rat) RFL32364RF Recombinant Full Length Rat 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-471)
Rhesus Macaque HTR2A-2175R Recombinant Rhesus monkey HTR2A Protein, His-tagged Mammalian Cell His
Rhesus Macaque HTR2A-1996R Recombinant Rhesus Macaque HTR2A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HTR2A-1996R-B Recombinant Rhesus Macaque HTR2A Protein Pre-coupled Magnetic Beads HEK293
Sus scrofa (Pig) RFL23544SF Recombinant Full Length Pig 5-Hydroxytryptamine Receptor 2A(Htr2A) Protein, His-Tagged E.coli expression system His Full Length (1-470)
Kit-0959 TR-FRET VDR Coactivator Assay Kit, goat N/A
Kit-1352 HTR2A U2OS β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HTR2A Related Research Area

HTR2A involved in several pathways and played different roles in them. We selected most pathways HTR2A participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayGNA15.4;EDNRB;TMEM8C;DRD1B;STIM1A;PLCD3A;PPP3R1;SLC25A31;ITPR1
Neuroactive ligand-receptor interactionDRD4B;NPFFR1L2;GRM1;NPY6R;PTGIR;F2RL3;HTR2C;P2RY10;MTNR1A
Gap junctionTUBA8L;TUBA3E;ADRB3B;TUBA4A;CSNK1DB;PRKCB;TUBA2;ADCY1A;MAP2K5
Serotonergic synapseGNG7;PLCB1;CYP2C54;GNAI2;GNG10;SLC18A2;GNB4;HTR7;GNG2
Inflammatory mediator regulation of TRP channelsMAP2K3;IL1R1;CYP2C55;HRH1;MAPK8;IL1RAP;CAMK2A;MAPK12;HTR2B

HTR2A has several biochemical functions, for example, 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, G-protein alpha-subunit binding, drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR2A itself. We selected most functions HTR2A had, and list some proteins which have the same functions with HTR2A. You can find most of the proteins on our site.

Function Related Protein
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine bindingHTR2A;HTR2C
G-protein alpha-subunit bindingLPAR1;LPAR3;OPRM1;HTR2A;F2RL1;PPP5C;AGTR1A;DRD1;ADRB2
drug bindingFABP1;P2RX2;FOLR1;HMGB2;SIGMAR1;CNR1;MT3;MTOR;CYP2D6
protein complex bindingRBX1;SKIL;OTOF;CASP8;RAN;VPS28;WASF1;ATM;CALY
serotonin bindingHTR2A;HTR1E;HTR1B;HTR2C;HTR3A;MAOA;HTR2B;HTR1F
serotonin receptor activityHTR7;HTR4;HTR6;HTR2A;HTR1AA;HTR1AB;HTR3C;HTR1D;HTR5A
virus receptor activityITGB5;TNFRSF4;SLC52A2;SELPLG;HTR2A;ANPEP;ITGB3;HLA-DRB1;SCARB2

HTR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR2A.

MPDZ; ketanserin

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