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Official Full Name immature colon carcinoma transcript 1
Background The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.
Synonyms ICT1; immature colon carcinoma transcript 1; peptidyl-tRNA hydrolase ICT1, mitochondrial; DS 1; Digestion substraction 1; DS1; Immature colon carcinoma transcript 1 protein; DS-1
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ICT1-395H Recombinant Human immature colon carcinoma transcript 1, His-tagged E.coli His
    Human ICT1-5313HCL Recombinant Human ICT1 293 Cell Lysate HEK293 N/A
    Mouse ICT1-7978M Recombinant Mouse ICT1 Protein Mammalian Cell His

    ICT1 involved in several pathways and played different roles in them. We selected most pathways ICT1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with ICT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitochondrial translation MRPL41; MRPS27; MRPS28; MRPL46; MRPL28; MRPL38; MRPL50; MRPS34; MRPS30; MRPS25
    Mitochondrial translation elongation MRPS28; MRPL46; MRPL40; MRPS25; MRPL47; MRPL54; DAP3; MRPL10; MRPS30; MRPS23
    Mitochondrial translation initiation MRPL40; MRPL53; MRPS22; MRPS33; MRPL28; MTIF3; MRPS23; MTFMT; MRPL47; MRPL46
    Mitochondrial translation termination MRPS25; MRPL47; MRPS31; PTCD3; MRPL42; MRPL55; MRPL41; MRPS23; MRPL51; MRPS22
    Organelle biogenesis and maintenance BBS1; IQCB1; MRPS23; TTC8; MTIF3; MRPL55; C10orf2; DYNLL2B; EXOC6; MRPS24

    ICT1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by ICT1 itself. We selected most functions ICT1 had, and list some proteins which have the same functions with ICT1. You can find most of the proteins on our site.

    Function Related Protein
    aminoacyl-tRNA hydrolase activity PTRH1; PTRHD1; PTRH2; C12orf65; ICT1
    ribosome binding ETF1; NAA16; RPSA; EIF2S1A; EIF2A; EIF2S1; EIF5A; EIF6; MTOR; CPEB1
    translation release factor activity, codon nonspecific ICT1; C12orf65
    NOT translation release factor activity, codon specific C12orf65; ICT1

    ICT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ICT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ICT1.

    MRPL3; DAP3; MRPL12; MCC; VHL; GTPBP10; MRPL38; a6nle7_human; grsf1; slc25a6; nipsnap1; sdha; oxa1l; mrps31; immt

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