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ICT1

  • Official Full Name

    immature colon carcinoma transcript 1

  • Overview

    The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.
  • Synonyms

    ICT1; immature colon carcinoma transcript 1; peptidyl-tRNA hydrolase ICT1, mitochondrial; DS 1; Digestion substraction 1; DS1; Immature colon carcinoma transcript 1 protein; DS-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ICT1-395H Recombinant Human immature colon carcinoma transcript 1, His-tagged E.coli His
Human ICT1-5313HCL Recombinant Human ICT1 293 Cell Lysate HEK293 N/A
Human ICT1-4369H Recombinant Human ICT1 protein, His-SUMO-tagged E.coli His-SUMO 30-206aa
Mouse ICT1-7978M Recombinant Mouse ICT1 Protein Mammalian Cell His
Mouse ICT1-4405M Recombinant Mouse ICT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ICT1-4405M-B Recombinant Mouse ICT1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ICT1 involved in several pathways and played different roles in them. We selected most pathways ICT1 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ICT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationTUFM;MRPL44;MRPL37;MRPL55;MRPL48;ICT1;MRPL41;MRPL10;MTRF1L
Mitochondrial translation elongationMRPL46;MRPL39;MRPS24;MRPL28;PTCD3;MRPL10;MRPS30;CHCHD1;MRPL38
Mitochondrial translation initiationMRPL47;MRPS27;MRPS33;MRPL40;MRPL37;MRPL48;DAP3;MRPS34;MRPS22
Mitochondrial translation terminationMRPS33;CHCHD1;MRPL10;MRPL50;MRPL42;MRPS36;MTRF1L;MRPL48;MRPL3
Organelle biogenesis and maintenanceNPHP4;TCTEX1D1;LZTFL1;IFT88;BBS12;POLG2;TCTN1;NPHP3;GFM1

ICT1 has several biochemical functions, for example, aminoacyl-tRNA hydrolase activity, ribosome binding, translation release factor activity, codon nonspecific. Some of the functions are cooperated with other proteins, some of the functions could acted by ICT1 itself. We selected most functions ICT1 had, and list some proteins which have the same functions with ICT1. You can find most of the proteins on our site.

Function Related Protein
aminoacyl-tRNA hydrolase activityPTRH2;C12orf65;PTRHD1;ICT1;PTRH1
ribosome bindingMTOR;EIF6;CPEB3;CPEB1B;ETF1A;OLA1;ETF1B;EIF2A;NARG1
translation release factor activity, codon nonspecificICT1;C12orf65
NOT translation release factor activity, codon specificC12orf65;ICT1

ICT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ICT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ICT1.

MRPL3; DAP3; MRPL12; MCC; VHL; GTPBP10; MRPL38; a6nle7_human; grsf1; slc25a6; nipsnap1; sdha; oxa1l; mrps31; immt

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