ifitm3
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  • Official Full Name
  • interferon induced transmembrane protein 3
  • Background
  • The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012]
  • Synonyms
  • IFITM3; interferon induced transmembrane protein 3; 1-8U; IP15; DSPA2b; interferon-induced transmembrane protein 3; dispanin subfamily A member 2b; interferon-inducible protein 1-8U;
Cat.#:IFITM3-5243HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFITM3 Protein, GST/His-tagged
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Cat.#:IFITM3-14073HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFITM3, GST-tagged
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Cat.#:IFITM3-26285HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFITM3, Fc Chimera
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Cat.#:IFITM3-26286THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFITM3, His-tagged
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Cat.#:IFITM3-2934HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFITM3, His-GST
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Cat.#:IFITM3-7338HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFITM3, Fc tagged
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Cat.#:IFITM3-8020MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IFITM3 Protein
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Cat.#:IFITM3-2994RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IFITM3 Protein
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Cat.#:IFITM3-1529HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFITM3 cell lysate
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Involved Pathway

IFITM3 involved in several pathways and played different roles in them. We selected most pathways IFITM3 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFITM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
EIF4E3; OSTN; ADAR; IRF6; TRIM48; MX2; EDA; GBP4; TRIM62; RASGRP4
Immune System
USP18; CD180; KIF18A; DEFB103A; UBE2J2; ACTR2B; DYNC1LI2; CMTM2A; CLEC2D; DTX3L
Interferon Signaling
OASL; IFITM2; IRF4; TRIM5; MX2; TRIM10; IFIT10; XAF1; IFIT11; TRIM3
Interferon alpha/beta signaling
BST2; SAMHD1; IRF9; IFI35; IFITM3; IFIT3; IFITM2; MX2; IFI6; IFI27

Protein Function

IFITM3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFITM3 itself. We selected most functions IFITM3 had, and list some proteins which have the same functions with IFITM3. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ZFP746; MEPE; CRELD2; Casp3; NRADD; STMN1; PPP1R3C; CAV1; MUL1; SCARB1

Interacting Protein

IFITM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFITM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFITM3.
NAMPT

IFITM3 Related Articles

Nakajima, A; Ibi, D; et al. Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes. EUROPEAN JOURNAL OF PHARMACOLOGY 745:166-175(2014).
Wrensch, F; Winkler, M; et al. IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms. VIRUSES-BASEL 6:3683-3698(2014).