INHA Protein, inhibin, alpha


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Official Full Name inhibin, alpha
Background Activin A is a homodimer of 14kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. The standard product used in this kit is recombinant Activin A, which is composed of two single chains of 116 amino acids with the molecular mass of 26KDa.
Synonyms Activin A; INHA; inhibin, alpha
    • Species :
    • Bovine
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • SUMO
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine INHA-582B Recombinant Bovine INHA Protein (227-360 aa), His-SUMO-tagged E.coli His/SUMO
    Human INHA/INHBA-32H Recombinant Human INHA/INHBA protein, His-tagged E.coli His
    Human INHA-110H Recombinant Human Inhibin A Reference standard N/A
    Human INHA-1842H Recombinant Human Inhibin, Alpha, His-tagged E.coli His
    Human INHA-2931H Recombinant Human Inhibin, Alpha, T7-tagged E.coli T7
    Human INHA-302H Recombinant Human Inhibin, Alpha, His-tagged Human His
    Human INHA-512H Recombinant Human INHA, GST-tagged Wheat Germ GST
    Human INHA-5204HCL Recombinant Human INHA 293 Cell Lysate HEK293 N/A
    Human INHA-579H Recombinant Human INHA Protein, His-tagged E.coli His
    Human INHA-8291H Recombinant Human INHA, His-tagged E.coli His
    Mouse Inha-492M Recombinant Mouse Inha CHO N/A
    Mouse Inha-580M Recombinant Mouse Inha Protein, His-tagged E.coli His
    Mouse INHA-8212M Recombinant Mouse INHA Protein Mammalian Cell His
    Rat INHA-3064R Recombinant Rat INHA Protein Mammalian Cell His
    Rat Inha-582R Recombinant Rat Inha Protein, His-tagged E.coli His
    Rhesus Macaque INHA-2271R Recombinant Rhesus monkey INHA Protein, His-tagged Mammalian Cell His
    Chicken INHA-2915C Recombinant Chicken INHA Mammalian Cell His
    Zebrafish INHA-4226Z Recombinant Zebrafish INHA Mammalian Cell His
    Cattle INHA-577C Recombinant Cattle INHA Protein, His-tagged E.coli His
    Pig INHA-581P Recombinant Pig INHA Protein, His-tagged E.coli His

    INHA involved in several pathways and played different roles in them. We selected most pathways INHA participated on our site, such as Glycoprotein hormones, Metabolism of proteins, Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with INHA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycoprotein hormones INHA; CGB5; CGB7; INHBAA
    Metabolism of proteins KLHDC3; EIF4H; ADAMTSL1; EID3; TIMM17B; PFDN4; VBP1; BET1; BCS1L; EXOC3
    Ovarian Infertility Genes DAZL; DMC1; INHA; ZP2; ZP3; NRIP1; SYNE2; GJA4; MSH5; NR5A1
    Peptide hormone biosynthesis CGB5; INHA; PCSK1; CGB7; INHBAA
    Peptide hormone metabolism EXOC8; ATP6AP2; CPB1; ACE; SLC38A8; O3far1; RAB27A; CPB2; BCHE; GPR120

    INHA has several biochemical functions, for example, cytokine activity, growth factor activity, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INHA itself. We selected most functions INHA had, and list some proteins which have the same functions with INHA. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity CCL20B; TGFB1; IL6; Ifnl2; BMP8A; IFNA5; CD70; RNF207B; Il2; IL33
    growth factor activity JAG2; FGF6A; FGF6B; BMP7A; MANF; OSM; CD320; PDGFA; MDK; CLCF1
    hormone activity PPY; PYYA; IGF2A; NPPC; IAPP; SMTLB; PRL8A9; ADM2; LEPA; EDN1
    inhibin binding ACVR2A; INHA; IGSF1; INHBA; ACVR1B
    protein binding ZW10; HIST1H4E; ATM; ZNF830; WNT2; EBF1; RAG1; NSUN4; NGFRB; LRRK2
    contributes_to protein binding INHA; MSH2; MLH1; POLR2A; TAF10; PAK1; ACVR2A; CPSF3L; CRY1A; TGFBR3
    protein heterodimerization activity THRA; INHA; HIST1H2BB; SDCBP; RXRA; H3F3B; NFE2L2A; KCNIP1; H2AFVB; NOTCH1
    receptor binding PAOX; SERPINE2; SNX17; NRG2B; HAO1; TAC1; Artn; GLA; TNFSF4; ANGPT2
    transforming growth factor beta receptor binding INHBC; INHBA; GDF3; GDF10; USP15; NDR2; GDF11; INHBAA; LFT1; GDF1

    INHA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INHA here. Most of them are supplied by our site. Hope this information will be useful for your research of INHA.


    Marino, FE; Risbridger, G; et al. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. MOLECULAR HUMAN REPRODUCTION 20:1223-1237(2014).
    Masieri, S; Trabattoni, D; et al. A role for Waldeyer's ring in immunological response to allergens. CURRENT MEDICAL RESEARCH AND OPINION 30:203-205(2014).

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