inha
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  • Official Full Name
  • inhibin, alpha
  • Background
  • Activin A is a homodimer of 14kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. The standard product used in this kit is recombinant Activin A, which is composed of two single chains of 116 amino acids with the molecular mass of 26KDa.
  • Synonyms
  • Activin A; INHA; inhibin, alpha
Cat.#:INHA-582BTag:His-SUMO
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine INHA Protein (227-360 aa), His-SUMO-tagged
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Cat.#:INHA-1842HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Inhibin, Alpha, His-tagged
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Cat.#:INHA-302HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Inhibin, Alpha, His-tagged
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Cat.#:INHA/INHBA-32HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHA/INHBA protein, His-tagged
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Cat.#:INHA-2931HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Inhibin, Alpha, T7-tagged
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Cat.#:INHA-512HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INHA, GST-tagged
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Cat.#:INHA-579HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHA Protein, His-tagged
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Cat.#:INHA-8291HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHA, His-tagged
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Cat.#:Inha-492MTag:
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse Inha
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Cat.#:Inha-580MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Inha Protein, His-tagged
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Cat.#:INHA-8212MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INHA Protein
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Cat.#:INHA-3064RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INHA Protein
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Cat.#:Inha-582RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Inha Protein, His-tagged
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Cat.#:INHA-2271RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey INHA Protein, His-tagged
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Cat.#:INHA-2915CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken INHA
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Cat.#:INHA-4226ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish INHA
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Cat.#:INHA-577CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle INHA Protein, His-tagged
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Cat.#:INHA-581PTag:His
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig INHA Protein, His-tagged
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Cat.#:INHA-5204HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human INHA 293 Cell Lysate
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Cat.#:INHA-110HTag:
Source (Host):Species:Human
Product nameRecombinant Human Inhibin A Reference standard
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Involved Pathway

INHA involved in several pathways and played different roles in them. We selected most pathways INHA participated on our site, such as Glycoprotein hormones, Metabolism of proteins, Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with INHA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycoprotein hormones
INHBAA; CGB5; CGB7; INHA
Metabolism of proteins
GALNTL2; CEACAM21; ADAMTS10; FURINA; FURINB; IGFBP4; FBXW9; ST6GAL2B; TOMM22; KLHDC3
Ovarian Infertility Genes
NRIP1; DAZL; MSH5; ZP3; GJA4; SYNE2; DMC1; NR5A1; INHA; ZP2
Peptide hormone biosynthesis
INHA; CGB5; CGB7; PCSK1; INHBAA
Peptide hormone metabolism
MBOAT4; CDX2; SLC30A6; CPB2; CPB1; SLC30A5; GRP; SPCS3; GPR120; ATP6AP2

Protein Function

INHA has several biochemical functions, for example, cytokine activity, growth factor activity, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INHA itself. We selected most functions INHA had, and list some proteins which have the same functions with INHA. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein CTF1; FLT3LG; IFNL3; IL17A; IFNW1; LIF; TNFSF12; BMP3; BMP10; TSLP
Function growth factor activity
Related Protein FGF14; MACC1; VEGFAB; BDNF; PDGFC; FGF18A; Artn; FGF8A; GDF2; LACRT
Function hormone activity
Related Protein AVP; PTHLHA; LRSAM1; EPO; THPO; PRL8A8; GH2; PRL7B1; C19orf80; FNDC5B
Function inhibin binding
Related Protein IGSF1; INHA; INHBA; ACVR2A; ACVR1B
Function protein binding
Related Protein WNT3; PPP2R2A; TNFSF14; RBFOX2; BDKRB1; TTC33; AMFR; STIM2; THOC1; MAFG
Function contributes_to protein binding
Related Protein CPSF3L; MSH2; MSH6; PAK1; TGFBR3; INHA; MEF2A; MLH1; CRY1A; TAF10
Function protein heterodimerization activity
Related Protein POLA2; HIST1H2B7; HIST1H3A; BAK1; BCL2L2; EGFR; TXLNG; HER5; HIST1H2BE; HIST2H2AC
Function receptor binding
Related Protein INHA; LAMA4; AMACR; MATK; FGF10A; CHRNA10; CRAT; HAND2; LRP6; FYNA
Function transforming growth factor beta receptor binding
Related Protein BMP8A; BMP4; LFT1; SPAW; USP15; LEFTY1; INHBE; BMP10; BMP15; BMP7

Interacting Protein

INHA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INHA here. Most of them are supplied by our site. Hope this information will be useful for your research of INHA.
SIAH1

INHA Related Articles

Marino, FE; Risbridger, G; et al. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. MOLECULAR HUMAN REPRODUCTION 20:1223-1237(2014).
Masieri, S; Trabattoni, D; et al. A role for Waldeyer's ring in immunological response to allergens. CURRENT MEDICAL RESEARCH AND OPINION 30:203-205(2014).