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INHA

  • Official Full Name

    inhibin, alpha

  • Overview

    Activin A is a homodimer of 14kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. The standard product used in this kit is recombinant Activin A, which is composed of two single chains of 116 amino acids with the molecular mass of 26KDa.
  • Synonyms

    Activin A; INHA; inhibin, alpha;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Mycobacterium tuberculosis
  • Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
  • Pig
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • SUMO
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human INHA-8291H Recombinant Human INHA, His-tagged E.coli His
Human INHA-302H Recombinant Human Inhibin, Alpha, His-tagged Human His
Human INHA-512H Recombinant Human INHA, GST-tagged Wheat Germ GST
Human INHA-1842H Recombinant Human Inhibin, Alpha, His-tagged E.coli His
Human INHA-2931H Recombinant Human Inhibin, Alpha, T7-tagged E.coli T7
Human INHA-579H Recombinant Human INHA Protein, His-tagged E.coli His Ala25~Cys363
Human INHA/INHBA-32H Recombinant Human INHA/INHBA protein, His-tagged E.coli His
Human INHA-5204HCL Recombinant Human INHA 293 Cell Lysate HEK293 N/A
Human INHA-110H Recombinant Human Inhibin A Reference standard N/A
Human INHA-301267H Recombinant Human INHA protein, GST-tagged E.coli GST Thr353-Ile366
Human INHA-561HF Recombinant Full Length Human INHA Protein, GST-tagged In Vitro Cell Free System GST 366 amino acids
Human INHA-3111H Recombinant Human INHA Protein (Ser233-Ile366), His tagged E.coli His Ser233-Ile366
Mouse Inha-492M Active Recombinant Mouse Inha CHO N/A
Mouse INHA-8212M Recombinant Mouse INHA Protein Mammalian Cell His
Mouse Inha-580M Recombinant Mouse Inha Protein, His-tagged E.coli His Trp240~Ile366
Mouse INHA-4547M Recombinant Mouse INHA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse INHA-4547M-B Recombinant Mouse INHA Protein Pre-coupled Magnetic Beads HEK293
Rat INHA-3064R Recombinant Rat INHA Protein Mammalian Cell His
Rat Inha-582R Recombinant Rat Inha Protein, His-tagged E.coli His Ala231-Ile366
Rat INHA-2720R Recombinant Rat INHA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat INHA-2720R-B Recombinant Rat INHA Protein Pre-coupled Magnetic Beads HEK293
Bovine INHA-582B Recombinant Bovine INHA Protein (227-360 aa), His-SUMO-tagged E.coli His/SUMO 227-360 aa
Cattle INHA-577C Recombinant Cattle INHA Protein, His-tagged E.coli His Ser227-Ile360
Mycobacterium tuberculosis inhA-4227M Recombinant Mycobacterium tuberculosis inhA protein, His-SUMO-tagged E.coli His-SUMO 1-269aa
Mycobacterium tuberculosis inhA-4228M Recombinant Mycobacterium tuberculosis inhA protein, His-tagged E.coli His 1-269aa
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) inhA-5717M Recombinant Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) inhA protein, His-tagged Yeast His 1-269aa
Rhesus Macaque INHA-2271R Recombinant Rhesus monkey INHA Protein, His-tagged Mammalian Cell His
Rhesus Macaque INHA-2092R Recombinant Rhesus Macaque INHA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque INHA-2092R-B Recombinant Rhesus Macaque INHA Protein Pre-coupled Magnetic Beads HEK293
Zebrafish INHA-4226Z Recombinant Zebrafish INHA Mammalian Cell His
Pig INHA-581P Recombinant Pig INHA Protein, His-tagged E.coli His Ala228~Ile364
Chicken INHA-2915C Recombinant Chicken INHA Mammalian Cell His
Chicken INHA-1061C Recombinant Chicken INHA Protein, His&GST-tagged E.coli N-His&GST Ser217-Val329
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • INHA Related Articles
  • INHA Related Research Area

INHA involved in several pathways and played different roles in them. We selected most pathways INHA participated on our site, such as Glycoprotein hormones, Metabolism of proteins, Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with INHA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycoprotein hormonesCGB5;CGB7;INHA;INHBAA
Metabolism of proteinsSPCS3;SEC61B;ARL2;SAE1;EXOC6;DDIT3;NOP56;PPP6C;SENP1
Ovarian Infertility GenesZP3;NRIP1;DMC1;INHA;MSH5;ZP2;NR5A1;DAZL;SYNE2
Peptide hormone biosynthesisINHA;CGB5;CGB7;PCSK1;INHBAA
Peptide hormone metabolismCGB7;RAB27A;DPP4;MBOAT4;ATP6AP2;CPB2;CPA3;INHBAA;CMA1

INHA has several biochemical functions, for example, cytokine activity, growth factor activity, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INHA itself. We selected most functions INHA had, and list some proteins which have the same functions with INHA. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCSF1B;TGFB1A;GM13288;IL36A;IFNG1-2;TNF;BMP7;GDF15;BMP2B
growth factor activityINHBA;FGF2;NGF;GDNF;FGF12A;MIA1;GMFG;NTF7;AMBN
hormone activityGIP;ADM2;GALP;STC1L;PTH;UTS1;CRH;TG;GPHA2
inhibin bindingINHA;INHBA;IGSF1;ACVR2A;ACVR1B
protein bindingORC1L;KIF22;HIST1H2AI;LRRC75A-AS1;TXNRD1;PDGFRB;RAB39A;SCNM1;SPDL1
contributes_to protein bindingPAK1;CRY1A;CPSF3L;MSH2;TAF10;MLH1;POLR2A;MEF2A;TGFBR3
protein heterodimerization activitySDCBP2;KCNN1;ATF2;USF2;TXLNG;SCGB2A1;TGFB2;PHC2B;KCNK3
receptor bindingBMP2;CADM3;PVRL2;NRG2B;ANKRD13C;WNT2BB;FLT3LG;CLCF1;KNG1
transforming growth factor beta receptor bindingNODAL;INHBE;GDF10;MSTN;GDF5;BMP10;BMP8A;BMP8B;GDF6B

INHA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INHA here. Most of them are supplied by our site. Hope this information will be useful for your research of INHA.

SIAH1

Marino, FE; Risbridger, G; et al. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. MOLECULAR HUMAN REPRODUCTION 20:1223-1237(2014).
Masieri, S; Trabattoni, D; et al. A role for Waldeyer's ring in immunological response to allergens. CURRENT MEDICAL RESEARCH AND OPINION 30:203-205(2014).
  • Q&As
  • Reviews

Q&As (7)

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Does INHA have implications in the context of cancer research?          04/22/2022

INHA's role in cancer research requires further investigation to determine its potential involvement in tumorigenesis.

What roles does INHA protein play in cellular processes?         12/28/2021

INHA protein serves various roles in cellular processes, potentially affecting cell growth, signaling, and development.

What is known about the expression patterns of INHA in different tissues? 10/18/2018

INHA may exhibit tissue-specific expression patterns, and its significance in various tissues is a subject of ongoing study.

Can you describe the specific functions of INHA in gene regulation? 09/28/2018

INHA may have functions related to gene regulation, influencing transcription and other cellular processes.

How does INHA contribute to cellular pathways and signaling?         09/24/2018

INHA likely contributes to cellular pathways and signaling cascades, impacting various cellular functions.

Are there any known interactions between INHA and other proteins or molecules? 04/29/2018

INHA may interact with other proteins or molecules, potentially affecting its cellular functions.

Have genetic mutations or alterations been linked to INHA? 12/23/2016

While INHA mutations or alterations are not extensively studied, they could be relevant to cellular processes and warrant further exploration.

Customer Reviews (3)

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Reviews
04/29/2022

    The product’s stability over extended periods was a significant advantage for our long-term research projects.

    04/16/2020

      Consistently achieving specific outcomes validated the pivotal role of the product in our research studies.

      09/11/2017

        The responsive customer support team provided quick resolutions to any queries or issues we encountered.

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