Recombinant Human Inhibin, Alpha, T7-tagged

• Cat.No.: INHA-2931H
• Product Overview: Recombinant Human INHA was produced inE.coliwith a T7 tag at N-terminus. MW = 39670 Da (19-366 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 19-366 a.a.
• Description: The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: INHA inhibin, alpha [ Homo sapiens ]
• Synonyms: INHA; inhibin, alpha; inhibin alpha chain; A-inhibin subunit
• Gene ID: 3623
• mRNA Refseq: NM_002191
• Protein Refseq: NP_002182
• MIM: 147380
• UniProt ID: P05111
• Chromosome Location: 2q33-q36
• Function: cytokine activity; growth factor activity; hormone activity; inhibin beta-A binding; protein binding; contributes_to protein binding; protein heterodimerization activity; receptor binding; signal transducer activity