inhbc
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  • Official Full Name
  • inhibin, beta C
  • Background
  • This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.
  • Synonyms
  • INHBC; inhibin, beta C; inhibin beta C chain; Activin beta C chain; IHBC; OTTHUMP00000242576; activin beta-C chain
Cat.#:INHBC-2401HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human INHBC Protein, MYC/DDK-tagged
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Cat.#:INHBC-5116HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INHBC Protein, GST-tagged
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Cat.#:INHBA&INHBC-737HTag:
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human INHBA&INHBC
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Cat.#:INHBC-116HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHBC, His-tagged
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Cat.#:INHBC-15867HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHBC, His-tagged
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Cat.#:INHBC-957HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INHBC Protein, His-tagged
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Cat.#:Inhbc-671MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Inhbc Protein, His-tagged
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Cat.#:INHBC-8215MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INHBC Protein
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Cat.#:INHBC-3067RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INHBC Protein
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Cat.#:Inhbc-672RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Inhbc Protein, His-tagged
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Cat.#:INHBC-346HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human INHBC lysate
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Involved Pathway

INHBC involved in several pathways and played different roles in them. We selected most pathways INHBC participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with INHBC were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
GM-CSF; TGFBR1; IL1R2; TNFRSF12A; IFNG; PLEKHO2; NGFRB; FIGF; Il6ra; IL10RA
TGF-beta signaling pathway
TGFBR2; BAMBI; ID1; TFDP1A; RPS6KB1B; ID2A; SMAD7; MYCB; FSTA; LEFTY2
Signaling pathways regulating pluripotency of stem cells
KLF4; FGF2; SMAD3; HNF1A; ACVR1; WNT6; GRB2; SMAD4; HESX1; DLX5

Protein Function

INHBC has several biochemical functions, for example, cytokine activity, growth factor activity, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INHBC itself. We selected most functions INHBC had, and list some proteins which have the same functions with INHBC. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein Ctf2; IFNG; NODAL; PRL7D1; IL26; Il23a; Il12b; IFNA2; TNFSF11; IL36RN; INHBB
Function growth factor activity
Related Protein GPI; KLK1B4; BMP8A; VHL; MSTNA; HBEGFA; OSM; LFT2; EGF; CSF3
Function hormone activity
Related Protein CRHR2; POMC; GALP; TSHB; RLN2; INHBE; FSD1; INSL5B; INS2; GCG
Function transforming growth factor beta receptor binding
Related Protein GDF15; BMP8A; LFT1; GDF6B; INHBB; BMP5; TGFB2; INHBAB; GDF9; MSTNB

INHBC Related Articles

Han, XF; Gu, LJ; et al. Effect of immunization against GnRH on hypothalamic and testicular function in rams. THERIOGENOLOGY 83:642-649(2015).
Marino, FE; Risbridger, G; et al. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. MOLECULAR HUMAN REPRODUCTION 20:1223-1237(2014).