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INTS4

  • Official Full Name

    integrator complex subunit 4

  • Overview

    INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).
  • Synonyms

    INTS4; integrator complex subunit 4; INT4; MGC16733; MST093; MSTP093; RGD1305036; OTTHUMP00000233860;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human INTS4-131H Recombinant Human INTS4, GST-tagged E.coli GST 1-331aa
Human INTS4-864HCL Recombinant Human INTS4 cell lysate N/A
Human INTS4-3534H Recombinant Human INTS4 protein, His-tagged E.coli His 1-331 aa
Human INTS4-5087H Recombinant Human INTS4 Protein, GST-tagged Wheat Germ GST
Human INTS4-5673HF Recombinant Full Length Human INTS4 Protein, GST-tagged In Vitro Cell Free System GST 963 amino acids
Mouse INTS4-8248M Recombinant Mouse INTS4 Protein Mammalian Cell His
Mouse INTS4-4568M Recombinant Mouse INTS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse INTS4-4568M-B Recombinant Mouse INTS4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • INTS4 Related Articles

INTS4 involved in several pathways and played different roles in them. We selected most pathways INTS4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INTS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

INTS4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS4 itself. We selected most functions INTS4 had, and list some proteins which have the same functions with INTS4. You can find most of the proteins on our site.

Function Related Protein
protein bindingCHRAC1;USP19;ABLIM1;RRM2;WDR77;FAM71C;SENP5;NDUFS1;RERE

INTS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS4.

HGS; USHBP1; ZMIZ2; PYGM; PPP2R1A; PPP2CB; Ppp2ca; PPP2CA; Ppp2r1a; VWA9

Oron, E; Mannervik, M; et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. DEVELOPMENT 129:4399-4409(2002).
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