Recombinant Human INTS4 Protein, GST-tagged

• Cat.No.: INTS4-5087H
• Product Overview: Human INTS4 full-length ORF ( NP_291025.3, 1 a.a. - 963 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 134.6 kDa
• AA Sequence: MAAHLKKRVYEEFTKVVQPQEEIAT KKLRLTKPSKSAALHIDLCKATSPA DALQYLLQFARKPVEAESVEGVVRI LLEHYYKENDPSVRLKIASLLGLLS KTAGFSPDCIMDDAINILQNEKSHQ VLAQLLDTLLAIGTKLPENQAIQMR LVDVACKHLTDTSHGVRNKCLQLLG NLGSLEKSVTKDAEGLAARDVQKII GDYFSDQDPRVRTAAIKAMLQLHER GLKLHQTIYNQACKLLSDDYEQVRS AAVQLIWVVSQLYPESIVPIPSSNE EIRLVDDAFGKICHMVSDGSWVVRV QAAKLLGSMEQVSSHFLEQTLDKKL MSDLRRKRTAHERAKELYSSGEFSS GRKWGDDAPKEEVDTGAVNLIESGA CGAFVHGLEDEMYEVRIAAVEALCM LAQSSPSFAEKCLDFLVDMFNDEIE EVRLQSIHTMRKISNNITLREDQLD TVLAVLEDSSRDIREALHELLCCTN VSTKEGIHLALVELLKNLTKYPTDR DSIWKCLKFLGSRHPTLVLPLVPEL LSTHPFFDTAEPDMDDPAYIAVLVL IFNAAKTCPTMPALFSDHTFRHYAY LRDSLSHLVPALRLPGRKLVSSAVS PSIIPQEDPSQQFLQQSLERVYSLQ HLDPQGAQELLEFTIRDLQRLGELQ SELAGVADFSATYLRCQLLLIKALQ EKLWNVAAPLYLKQSDLASAAAKQI MEETYKMEFMYSGVENKQVVIIHHM RLQAKALQLIVTARTTRGLDPLFGM CEKFLQEVDFFQRYFIADLPHLQDS FVDKLLDLMPRLMTSKPAEVVKILQ TMLRQSAFLHLPLPEQIHKASATII EPAGESDNPLRFTSGLVVALDVDAT LEHVQDPQNTVKVQVLYPDGQAQMI HPKPADFRNPGPGRHRLITQVYLSH TAWTEACQVEVRLLLAYNSSARIPK CPWMEGGEMSPQVETSIEGTIPFSK PVKVYIMPKPARR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INTS4 integrator complex subunit 4 [ Homo sapiens ]
• Official Symbol: INTS4
• Synonyms: INTS4; integrator complex subunit 4; INT4; MGC16733; MST093; MSTP093
• Gene ID: 92105
• mRNA Refseq: NM_033547
• Protein Refseq: NP_291025
• MIM: 611348
• UniProt ID: Q96HW7