invs
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  • Official Full Name
  • inversin
  • Background
  • This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012]
  • Synonyms
  • INVS; inversin; INV; NPH2; NPHP2; nephrocystin-2; inversion of embryonic turning; inversion of embryo turning homolog;
Cat.#:INVS-5082HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INVS Protein, GST-tagged
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Cat.#:INVS-395HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human INVS
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Cat.#:INVS-7870HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INVS protein, His & T7-tagged
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Cat.#:INVS-6120CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken INVS
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Cat.#:INVS-9436ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish INVS
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Involved Pathway

INVS involved in several pathways and played different roles in them. We selected most pathways INVS participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with INVS were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
LRP6; CUL1A; FZD7A; CTNNBIP1; PLCB4; PRKACBA; SIAH2L; PLCB1; SFRP2; RHOAD

Protein Function

INVS has several biochemical functions, for example, calmodulin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INVS itself. We selected most functions INVS had, and list some proteins which have the same functions with INVS. You can find most of the proteins on our site.
Function
Related Protein
Function calmodulin binding
Related Protein RASGRF2B; AEBP1; PHKA1; CAMK1GA; TRPV4; MAPKAPK5; MYH1E; REM1; GEM; RGS2
Function protein binding
Related Protein DGKQ; TAGLN; KRT83; VASN; EPHA3; RAP1GAP; XAGE2; NFKB2; TEX13A; PTS

INVS Related Articles

Widman, DG; Frolov, I; et al. Third-Generation Flavivirus Vaccines Based on Single-Cycle, Encapsidation-Defective Viruses. ADVANCES IN VIRUS RESEARCH, VOL 72 72:77-126(2008).
SODEIK, B; DOMS, RW; et al. ASSEMBLY OF VACCINIA VIRUS - ROLE OF THE INTERMEDIATE COMPARTMENT BETWEEN THE ENDOPLASMIC-RETICULUM AND THE GOLGI STACKS. JOURNAL OF CELL BIOLOGY 121:521-541(1993).