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Official Full Name importin 8
Synonyms IPO8; importin 8; importin-8; Imp 8; Imp8; Importin8; IPO 8; Ran binding protein 8; RAN BP8; RANBP 8; RANBP8
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IPO8-5075H Recombinant Human IPO8 Protein, GST-tagged Wheat Germ GST
    Mouse Ipo8-199M Recombinant Mouse Ipo8 Protein, His/GST-tagged E.coli His/GST
    Mouse IPO8-8266M Recombinant Mouse IPO8 Protein Mammalian Cell His
    Rhesus Macaque IPO8-2286R Recombinant Rhesus monkey IPO8 Protein, His-tagged Mammalian Cell His
    Zebrafish IPO8-3874Z Recombinant Zebrafish IPO8 Mammalian Cell His

    IPO8 involved in several pathways and played different roles in them. We selected most pathways IPO8 participated on our site, such as Gene Expression, Gene Silencing by RNA, Transcriptional regulation by small RNAs, which may be useful for your reference. Also, other proteins which involved in the same pathway with IPO8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression COX16; MAEL; CCDC76; HNRNPR; PRPF8; AGO3B; GM3258; MED13B; HBXIP; MBD3B
    Gene Silencing by RNA TNRC6B; FKBP6; TSNAX; MYBL1; AGO3B; PIWIL4; TSN; HENMT1; EIF2C3; TDRD1
    Transcriptional regulation by small RNAs IPO8; DPY19L2

    IPO8 has several biochemical functions, for example, ATPase activity, coupled to transmembrane movement of substances, Ran GTPase binding, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IPO8 itself. We selected most functions IPO8 had, and list some proteins which have the same functions with IPO8. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activity, coupled to transmembrane movement of substances ABCA5; IPO8; Abcb1b; ABCA7; ATP6V1D; ABCG3; ABCD3B; ABCA1B; ABCD4; ABCC11
    Ran GTPase binding RANGRF; XPO6; DPY19L2; KPNB1; IPO8; NUTF2; RANBP1; IPO4; TNPO1; XPO5
    protein transporter activity AP2A2; KPNA6; ZFYVE16; RAMP1; DPY19L2; AP4B1; XPO6; RANGRF; AP1S3; IPO5

    IPO8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IPO8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IPO8.

    Irs1; Rpgrip1l

    Moriyama, T; Mizuguchi, C; et al. Generation of Rat Monoclonal Antibody Specific for Mouse Importin alpha 8. HYBRIDOMA 30:303-306(2011).
    Yoneda, Y; et al. Monoclonal Antibody 3F2 Against Mouse Importin alpha 8. HYBRIDOMA 30:315-315(2011).
    Pryor, MJ; Rawlinson, SM; et al. Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection. TRAFFIC 8:795-807(2007).
    Subramaniam, PS; Larkin, J; et al. The COOH-terminal nuclear localization sequence of interferon gamma regulates STAT1 alpha nuclear translocation at an intracellular site. JOURNAL OF CELL SCIENCE 113:2771-2781(2000).

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