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ITGA8

  • Official Full Name

    integrin, alpha 8

  • Overview

    Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene.
  • Synonyms

    ITGA8; integrin, alpha 8; integrin alpha-8; Integrin alpha 8; ITGA 8; OTTHUMP00000019207;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • Flag|His
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ITGA8-4118H Recombinant Human ITGA8, flag & His tagged Human Cell Flag/His
Human ITGA8 & ITGB1-1876HCL Recombinant Human ITGA8 & ITGB1 cell lysate Human Cell N/A
Human ITGA8-287H Recombinant Human ITGA8 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human ITGA8-4993H Recombinant Human ITGA8 Protein, GST-tagged Wheat Germ GST
Human ITGA8-1313HFL Recombinant Full Length Human HSPA15 Protein, C-Flag-tagged Mammalian cells Flag
Human ITGA8-2613H Recombinant Human ITGA8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ITGA8-1212H-B Recombinant Human ITGA8 Protein Pre-coupled Magnetic Beads HEK293
Human ITGA8-1212H Recombinant Human ITGA8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ITGA8-246H Recombinant Human ITGA8 Protein, His/GST-tagged E.coli His/GST Asp907~Ala1063
Mouse ITGA8-8354M Recombinant Mouse ITGA8 Protein Mammalian Cell His
Mouse ITGA8-4639M-B Recombinant Mouse ITGA8 Protein Pre-coupled Magnetic Beads HEK293
Mouse ITGA8-4639M Recombinant Mouse ITGA8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Itga8-3598M Recombinant Mouse Itga8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish ITGA8-6497Z Recombinant Zebrafish ITGA8 Mammalian Cell His
Chicken ITGA8-6840C Recombinant Chicken ITGA8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ITGA8 Related Articles
  • ITGA8 Related Research Area

ITGA8 involved in several pathways and played different roles in them. We selected most pathways ITGA8 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PIK-Akt signaling pathwayTCL1B4;TCL1A;DDIT4;IL6;FGFR2;LPAR4;Kitl;PGF;CRTC2
Focal adhesionPAK1;PARVG;THBS3;ITGB3;RAC1A;THBS4A;ROCK2;RHOAC;COL4A6
ECM-receptor interactionITGB6;COL27A1;ITGA9;ITGA3B;LAMB1;COL5A1;ITGB1A;FN1;COL5A2
Cell adhesion molecules (CAMs)CD40LG;NEGR1;NLGN4X;PVRL2;CLDN7A;NRXN1A;CLDN20;ITGB1B.2;ITGA6
Regulation of actin cytoskeletonMAP2K2A;FGF19;MYH9;FGD3;INSB;ARHGEF4;RAF1B;GSN;ITGAL
Hypertrophic cardiomyopathy (HCM)TPM3;DAG1;ITGB3;TPM1;ATP2A2;ITGB4;SGCG;DES;CACNG3
Arrhythmogenic right ventricular cardiomyopathy (ARVC)AASS;ITGA5;ACTN3;SLC8A1;SGCB;ITGB6;ITGB3;DSG2;DSP
Dilated cardiomyopathySGCA;TNNC1;ITGB6;ATP2A2;CACNG8;CACNG3;ITGA6;CACNB2;ITGA2

ITGA8 has several biochemical functions, for example, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA8 itself. We selected most functions ITGA8 had, and list some proteins which have the same functions with ITGA8. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingZBED5;ZNF718;ATP2C2;ZKSCAN1;MTMR4;AARS2;PRDM15;Trl;ZNF484

ITGA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA8.

Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Shi, L; Zhang, LC; et al. Expression, purification and renaturation of truncated human integrin beta 1 from inclusion bodies of Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 107:13-19(2015).
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