l3mbtl1
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  • Official Full Name
  • l(3)mbt-like 1 (Drosophila)
  • Background
  • This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms
  • L3MBTL1; l(3)mbt-like 1 (Drosophila); l(3)mbt (Drosophila) like , l(3)mbt like (Drosophila) , L3MBTL; lethal(3)malignant brain tumor-like protein 1; dJ138B7.3; DKFZp586P1522; KIAA0681; lethal (3) malignant brain tumor l(3); RGD1307316; H-L(3)MBT; H-l(3)mbt protein; L(3)mbt protein homolog; L(3)mbt-like; L3MBT; LMBL1_HUMAN; L3MBTL
Cat.#:L3MBTL1-124HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human L3MBTL1 Protein, GST-tagged
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Cat.#:L3MBTL1-125HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human L3MBTL1 Protein, His-tagged
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Cat.#:L3MBTL1-254HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human L3MBTL1 protein, GST-tagged
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Cat.#:L3MBTL1-255HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CBX1 protein, GST-tagged
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Cat.#:L3MBTL1-8916MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse L3MBTL1 Protein
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Cat.#:L3MBTL1-964HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human L3MBTL1 cell lysate
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Cat.#:Kit-1779Tag:N/A
Source (Host):Species:
Product nameL3MBTL1 Inhibitor Screening Assay Kit
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Cat.#:Kit-1780Tag:N/A
Source (Host):Species:
Product nameL3MBTL1 TR-FRET Assay Kit
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Cat.#:Kit-1966Tag:N/A
Source (Host):Species:
Product nameL3MBTL1 MBT Domains TR-FRET Assay Kit
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Protein Function

L3MBTL1 has several biochemical functions, for example, SAM domain binding, chromatin binding, histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by L3MBTL1 itself. We selected most functions L3MBTL1 had, and list some proteins which have the same functions with L3MBTL1. You can find most of the proteins on our site.
Function
Related Protein
Function SAM domain binding
Related Protein L3MBTL1
Function chromatin binding
Related Protein TOP2A; DNAJC2; NR5A1; MKRN1; SSRP1; MTA1; WDR82; EGFR; SP100; CREB3
Function histone binding
Related Protein HIST1H4L; H3F3B; RNF168; DTX3L; ASF1B; ATAD2; UHRF1; PYGO2; ZMYND11; PRMT7
Function identical protein binding
Related Protein NEFL; LYZ; GRB7; ROBO1; COIL; ORAI1; RPE; COL2A1; NIF3L1; BRAP
Function methylated histone binding
Related Protein LOXL2; L3MBTL1; PHF8; KAT8; JHDM1D; MSH6; ING4; TP53BP1; CCDC101; GLYR1
Function nucleosomal histone binding
Related Protein VRK1; UHRF1; L3MBTL1
Function nucleosome binding
Related Protein DNTTIP1; NOC2L; HP1BP3; ARID1A; ZNHIT1; RNF4; L3MBTL1; MUM1; RNF168; SMARCA5
Function protein binding
Related Protein PMM2; SPAG8; SRSF2; MED1; TMBIM6; RIC8A; SENP5; LUC7L2; AMELX; SHROOM2
Function transcription factor activity, sequence-specific DNA binding
Related Protein HELT; HMGB2; NFIL3-6; TCF7L1A; ZFP628; NR6A1B; HMGA1B; HOXB6; SRF; TRIM25
Function zinc ion binding
Related Protein VAT1L; TRIM15; RNF11B; RNF183; RNF10; CNBP; ZCCHC16; GATAD2A; MYT1LA; USP13

Interacting Protein

L3MBTL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with L3MBTL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of L3MBTL1.
HIST2H4B; HIST1H1E; HIST1H3D; RB1; CBX3

L3MBTL1 Related Articles

Carlson, SM; Moore, KE; et al. Proteome-wide enrichment of proteins modified by lysine methylation. NATURE PROTOCOLS 9:37-50(2014).
Edwards, CR; Dang, WW; et al. Histone H4 Lysine 20 of Saccharomyces cerevisiae Is Monomethylated and Functions in Subtelomeric Silencing. BIOCHEMISTRY 50:10473-10483(2011).