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LCMT1

  • Official Full Name

    leucine carboxyl methyltransferase 1

  • Overview

    LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic;subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 (PubMed 10600115)).
  • Synonyms

    LCMT1; leucine carboxyl methyltransferase 1; Lcmt; LCMT-1; AL033290; MGC11807;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LCMT1-187H Active Recombinant Human LCMT1 protein, GST-tagged Insect Cell GST
Human LCMT1-1563H Recombinant Human Leucine Carboxyl Methyltransferase 1, His-tagged E.coli His
Human LCMT1-4803HCL Recombinant Human LCMT1 293 Cell Lysate HEK293 N/A
Human LCMT1-5889H Recombinant Human LCMT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Lcmt1-3759M Recombinant Mouse Lcmt1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat LCMT1-3366R Recombinant Rat LCMT1 Protein Mammalian Cell His
Rat LCMT1-3022R Recombinant Rat LCMT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LCMT1-3022R-B Recombinant Rat LCMT1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey LCMT1-649C Recombinant Cynomolgus LCMT1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey LCMT1-395C-B Recombinant Cynomolgus Monkey LCMT1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey LCMT1-395C Recombinant Cynomolgus Monkey LCMT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LCMT1-2475R Recombinant Rhesus monkey LCMT1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LCMT1-2296R Recombinant Rhesus Macaque LCMT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LCMT1-2296R-B Recombinant Rhesus Macaque LCMT1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LCMT1-1359Z Recombinant Zebrafish LCMT1 Mammalian Cell His
Chicken LCMT1-1318C Recombinant Chicken LCMT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LCMT1 Related Articles

LCMT1 involved in several pathways and played different roles in them. We selected most pathways LCMT1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LCMT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

LCMT1 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity, protein C-terminal carboxyl O-methyltransferase activity, protein C-terminal leucine carboxyl O-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LCMT1 itself. We selected most functions LCMT1 had, and list some proteins which have the same functions with LCMT1. You can find most of the proteins on our site.

Function Related Protein
S-adenosylmethionine-dependent methyltransferase activityRRP8;LCMT2;SUV39H1;WBSCR27;TPMT.1;ASMT2;PRMT8;PRMT8B;PRMT7
protein C-terminal carboxyl O-methyltransferase activityMETTL7B;PRDM13;METTL23;METTL21A;DIMT1;TRMT10B;NDUFAF5;RNMTL1B;METTL8
protein C-terminal leucine carboxyl O-methyltransferase activityPRDM13;PRMT8B;TRMT10C;TRMT10B;PRDM12;METTL8;FBLL1;METTL21A;RNMTL1B
protein bindingENDOG;PSMD3;ZNF187;TIMM50;AKR1C1;WDR11;CRTC2;PSMC3;ARHGEF6

LCMT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCMT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCMT1.

FXR2; solA; TAB1

Longin, S; Zwaenepoel, K; et al. Spatial control of protein phosphatase 2A (de)methylation. EXPERIMENTAL CELL RESEARCH 314:68-81(2008).
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