lta4h
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  • Official Full Name
  • leukotriene A4 hydrolase
  • Background
  • Hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). The enzyme also has some peptidase activity.
  • Synonyms
  • LTA4H; leukotriene A4 hydrolase; leukotriene A-4 hydrolase; LTA-4 hydrolase; FLJ17564
Cat.#:LTA4H-1221HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human LTA4H Protein, MYC/DDK-tagged
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Cat.#:LTA4H-4594HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human LTA4H Protein, GST-tagged
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Cat.#:LTA4H-305HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human LTA4H, His tagged
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Cat.#:LTA4H-306HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human LTA4H Protein, His-tagged
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Cat.#:LTA4H-315HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human LTA4H Protein, His-tagged
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Cat.#:LTA4H-51HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LTA4H, His-tagged
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Cat.#:LTA4H-84HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LTA4H protein, T7/His-tagged
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Cat.#:Lta4h-7956MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lta4h protein, His & T7-tagged
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Cat.#:LTA4H-859MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse LTA4H, His tagged
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Cat.#:LTA4H-1381CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LTA4H
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Cat.#:LTA4H-12477ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LTA4H
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Cat.#:LTA4H-731HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human LTA4H cell lysate
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Cat.#:LTA4H-653MCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse LTA4H cell lysate
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Involved Pathway

LTA4H involved in several pathways and played different roles in them. We selected most pathways LTA4H participated on our site, such as Arachidonic acid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTA4H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arachidonic acid metabolism
PLA2G4D; CYP2AD3; CYP2P10; PTGDSA; CYP2B19; PLA2G4AA; GPX6; GGT5; AWAT1; CYP4A12A
Metabolic pathways
MTMR6; PCYT2; UGT2B15; ALOX8; UGT1A9; CHPT1; MINPP1A; PMM2; PDXK; NDUFC1

Protein Function

LTA4H has several biochemical functions, for example, aminopeptidase activity, epoxide hydrolase activity, leukotriene-A4 hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTA4H itself. We selected most functions LTA4H had, and list some proteins which have the same functions with LTA4H. You can find most of the proteins on our site.
Function
Related Protein
Function aminopeptidase activity
Related Protein METAP1D; METAP2; DNPEP; TPP2; XPNPEP3; PHEX; METAP2A; TRHDE; CTSL2; ENPEP
Function epoxide hydrolase activity
Related Protein EPHX3; Npepo; LTA4H; EPHX2; RNPEP; EPHX4; EPHX1
Function leukotriene-A4 hydrolase activity
Related Protein LTA4H
Function metalloaminopeptidase activity
Related Protein ERAP1; LNPEP; METAP2A; ERAP2; Npepo; ANPEP; TRHDE; RNPEP; XPNPEP1; ANPEPA
Function peptidase activity
Related Protein ST14A; KLK1B16; UNC5CL; NAALADL1; PARLA; TPP1; PRSS42; MMP14B; KLK1B5; USP43A
Function peptide binding
Related Protein Npepo; ENPEP; RNPEPL1; LTA4H; QRFPR; THOP1; ERAP2; PPIB; BDKRB1; GPR22
Function poly(A) RNA binding
Related Protein HSP90AB1; MRPL37; RPGR; RPS21; HNRNPA0; RBM15B; HNRNPH1; NOL6; HNRNPH3; NAP1L1
Function protein binding
Related Protein TMEM149; ADORA1; OCLN; TIMP1; SEC61B; CTRC; LHFPL5; AMBP; CDK7; CD22
Function zinc ion binding
Related Protein EP300; ADAM5P; KLF7; SOD3A; ZMYM2; PEX12; TRIM41; RARAA; CHURC1; RXRB

Interacting Protein

LTA4H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTA4H here. Most of them are supplied by our site. Hope this information will be useful for your research of LTA4H.
TINF2; GH1; MCC; HLA-B; HLA-C; IKBKE; DDA1; UBA5; ARPC3; TMEM62; q8d0m8_yerpe