magea1
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  • Official Full Name
  • melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
  • Background
  • Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues.
  • Synonyms
  • MAGEA1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); MAGE1; melanoma-associated antigen 1; cancer/testis antigen family 1; member 1; CT1.1; melanoma antigen family A 1; melanoma antigen MAGE 1; melanoma associated antigen 1; melanoma associated antigen MZ2 E; MGC9326; antigen MZ2-E; MAGE-1 antigen; melanoma antigen MAGE-1; cancer/testis antigen 1.1; melanoma-associated antigen MZ2-E; cancer/testis antigen family 1, member 1
Cat.#:MAGEA1-170HTag:FLAG
Source (Host):HEK293Species:Human
Product nameRecombinant Human MAGEA1 Protein, FLAG-tagged
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Cat.#:MAGEA1-171HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MAGEA1 Protein, MYC/DDK-tagged
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Cat.#:MAGEA1-28HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAGEA1 Protein, GST-tagged
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Cat.#:MAGEA1-1653HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAGEA1 protein, His & T7-tagged
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Cat.#:MAGEA1-28505THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAGEA1
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Cat.#:MAGEA1-157HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAGEA1
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Cat.#:MAGEA1-4558HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MAGEA1 293 Cell Lysate
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Involved Pathway

MAGEA1 involved in several pathways and played different roles in them. We selected most pathways MAGEA1 participated on our site, such as Delta-Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Delta-Notch Signaling Pathway
TLE1; TUBB3; HES6; MAGEA1; ASCL1; SMAD3B; CNTF; ASCL1A; SAP30; YY1A

Protein Function

MAGEA1 has several biochemical functions, for example, histone deacetylase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA1 itself. We selected most functions MAGEA1 had, and list some proteins which have the same functions with MAGEA1. You can find most of the proteins on our site.
Function
Related Protein
Function histone deacetylase binding
Related Protein HDAC9; HDAC5; BRMS1; ZMYND15; BRMS1LA; ZNF703; RFXANK; KPNA2; MEF2D; TFAP4
Function protein binding
Related Protein USP44; FAM59A; CCDC121; RSRC2; CCKBR; GLYR1; SFMBT1; DCP1A; FBN1; MAPK1

Interacting Protein

MAGEA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA1.
TRIM31; MIEF1; SELPLG; SFN; TRIM31; PBX3