MED11 Protein, mediator complex subunit 11

MED11

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MED11

Official Full Name mediator complex subunit 11
Background MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Synonyms MED11; mediator complex subunit 11; HSPC296; mediator of RNA polymerase II transcription subunit 11; mediator of RNA polymerase II transcription, subunit 11 homolog;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MED11-4480H Recombinant Human MED11 Protein, GST-tagged Wheat Germ GST
    Human MED11-874H Recombinant Human MED11 Protein, His-tagged E.coli His
    Mouse MED11-9681M Recombinant Mouse MED11 Protein Mammalian Cell His
    Rhesus Macaque MED11-2717R Recombinant Rhesus monkey MED11 Protein, His-tagged Mammalian Cell His
    Zebrafish MED11-7468Z Recombinant Zebrafish MED11 Mammalian Cell His

    MED11 involved in several pathways and played different roles in them. We selected most pathways MED11 participated on our site, such as Mus musculus biological processes, Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mus musculus biological processes MED11; SYCP1; POT1A; KLF5; SYCE2; SYNE2; SUN2
    Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes MED11; KLF5

    MED11 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, protein binding, contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED11 itself. We selected most functions MED11 had, and list some proteins which have the same functions with MED11. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II transcription cofactor activity CNOT2; MED18; MED19A; MED1; NKX2; MED13; MED13A; MED8; MED11; NKX2-5
    protein binding MBL2; FAM13C; BATF3; FBXL3; Car4; TBXAS1; ZFPM1; SNX33; ZNF227; VEGFB
    contributes_to ubiquitin protein ligase activity FBXL14A; CUL2; CUL3; MED12; FBXL18; FBXL22; MED11; ANAPC2; FBXL14; FBXL20

    MED11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED11.

    MED6; MED22; MED27; MED18; Med30; Med8; MED28; MED17; MED29; Ywhae; Cdk9

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