metap1
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  • Official Full Name
  • methionyl aminopeptidase 1
  • Background
  • Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.
  • Synonyms
  • METAP1; methionyl aminopeptidase 1; methionine aminopeptidase 1; KIAA0094; MAP1A; MetAP1A; Peptidase M; DKFZp781C0419; MAP 1; MetAP 1; Peptidase M 1
Cat.#:METAP1-4416HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human METAP1 Protein, GST-tagged
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Cat.#:METAP1-945HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human METAP1 Protein, MYC/DDK-tagged
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Cat.#:METAP1-1960HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Methionyl Aminopeptidase 1, His-tagged
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Cat.#:METAP1-15849HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human METAP1, His-tagged
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Cat.#:METAP1-202HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human METAP1 Protein, His-tagged
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Cat.#:METAP1-307HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human METAP1, Fc tagged
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Cat.#:NUDT16-151HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT16 Protein, GST-tagged
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Cat.#:NUDT16-152HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT16 Protein, His-tagged
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Cat.#:NUDT16-237HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT16 protein, T7/His-tagged
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Cat.#:NUDT16-954HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT16, His-tagged
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Cat.#:NUDT16-10966MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NUDT16 Protein
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Cat.#:METAP1-2735RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey METAP1 Protein, His-tagged
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Cat.#:NUDT16-3125RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NUDT16 Protein, His-tagged
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Cat.#:METAP1-2823CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken METAP1
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Cat.#:METAP1-3070ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish METAP1
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Cat.#:METAP1-2887HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human METAP1 cell lysate
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Cat.#:NUDT16-447HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human NUDT16 lysate
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Involved Pathway

METAP1 involved in several pathways and played different roles in them. We selected most pathways METAP1 participated on our site, such as Inactivation, recovery and regulation of the phototransduction cascade, Signal Transduction, The phototransduction cascade, which may be useful for your reference. Also, other proteins which involved in the same pathway with METAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Inactivation, recovery and regulation of the phototransduction cascade
NMT1; GRK7; NMT2; GNB5A; METAP2; NMT1B; GUCA1E; METAP2B; METAP1; RHOL
Signal Transduction
ZNRF3; FST; CCDC88C; SOX32; INSL3; ARHGAP12; STARD8; NEDD8; OTULINB; RBBP5
The phototransduction cascade
METAP2B; NMT1A; METAP1; GUCA1E; GRK7; PPEF1; NMT1B; SAGB; RLN1; METAP2A
Visual phototransduction
MYO7AA; BCO2L; RPE65B; APOA4B.2; METAP2B; RPE65A; CNGA1; RLN1; LRP10; GUCA1E

Protein Function

METAP1 has several biochemical functions, for example, aminopeptidase activity, metal ion binding, metalloexopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by METAP1 itself. We selected most functions METAP1 had, and list some proteins which have the same functions with METAP1. You can find most of the proteins on our site.
Function
Related Protein
Function aminopeptidase activity
Related Protein XPNPEP2; METAP2A; XPNPEP3; LTA4H; ENPEP; Npepo; XPNPEP1; DPP9; CTSL2; METAP2B
Function metal ion binding
Related Protein LOC780933; ANKFY1; CBS; ZBTB22; RAF1A; KDM4D; PPARDB; BAK1; CA15B; TNNC1
Function metalloexopeptidase activity
Related Protein DPEP2; METAP1D; ERAP1; NUDT16; DPEP3; RNPEP; METAP2B; METAP1; LAP3; METAP2A

Interacting Protein

METAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with METAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of METAP1.
CBWD1; SMAD9; HNRNPU

METAP1 Related Articles

Ahsan, F; Arif, A; et al. Characterization and bioassay of post-translationally modified interferon alpha-2b expressed in Escherichia coli. JOURNAL OF BIOTECHNOLOGY 184:11-16(2014).
Poreba, M; Gajda, A; et al. S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors. BIOCHIMIE 94:704-710(2012).