|Official Full Name||makorin ring finger protein 1|
|Background||The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of;intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the;MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000 (PubMed 10843807)).|
|Synonyms||MKRN1; makorin ring finger protein 1; E3 ubiquitin-protein ligase makorin-1; RNF61; RING finger protein 61; FLJ21334|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
MKRN1 involved in several pathways and played different roles in them. We selected most pathways MKRN1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MKRN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||GAN; CLEC2D; LILRB2; CREB1; NCR3LG1; PTBP3; FGF20A; LRR1; CREB1B; EVL|
|Antigen processing: Ubiquitination &||RBCK1; RNF14; TRIM41; TRIM63; ASB11; LRSAM1; ATG7; GAN; TPP2; RNF34|
|Proteasome degradation||ASB6; ASB14; KLHL21; TRIM69; ASB11; ASB8; UBE2F; RNF111; LRSAM1; TRIM11|
|Class I MHC mediated antigen processing &||RNF19B; UBE2V1; LRR1; UFL1; STUB1; LTN1; ASB17; B2ML; TRIM69; TRIM63|
|presentation||ASB13; KLHL21; ASB3; UBE2U; TRIM63; TRIM39; ARIH2; ASB18; SH3RF1; RNF123|
|Immune System||SH2D1B; SIGLEC11; DYNC1I2; PELI3; IFI6; GRAP2B; LRSAM1; TRIM63; HBL3; MB21D1|
MKRN1 has several biochemical functions, for example, chromatin binding, ligase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKRN1 itself. We selected most functions MKRN1 had, and list some proteins which have the same functions with MKRN1. You can find most of the proteins on our site.
|chromatin binding||ATXN7; LDB2A; YBX1; NCAPD3; SIRT2; NIPBL; MBD1; TCF3; MLH3; MEF2A|
|ligase activity||PET112L; RFWD3; MARCH9; UNKL; TRIML1; RNF144B; SHPRH; TTLL4; TRIM8; RANBP2|
|poly(A) RNA binding||RBM38; RSL24D1; RPLP0; FLNA; RPL19; DUS3L; FLYWCH2; HMGN2; TPT1; CLNS1A|
|protein binding||CLK1; SERPINA3K; ADCK3; TRPC6; CRP; TGIF2LY; RUVBL2; PGM2; SELP; PINX1|
|ubiquitin-protein transferase activity||UBR1; RBCK1; MARCH2; UBE2W; HECW2; PDZRN3B; NLRC4; RNF181; TOPORS; BRAP|
|zinc ion binding||MYLIP; GALT; DPYS; MICAL1; MAN2B2; WTIP; TRAF1; NR1H3; BIRC7; RNF31|
MKRN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKRN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MKRN1.
TP53; CDKN1A; UBC; UBE2D3; ctc; X; UBE2W; EXOSC8; DUSP23