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MKRN1

  • Official Full Name

    makorin ring finger protein 1

  • Overview

    The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of;intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the;MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000 (PubMed 10843807)).
  • Synonyms

    MKRN1; makorin ring finger protein 1; E3 ubiquitin-protein ligase makorin-1; RNF61; RING finger protein 61; FLJ21334;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MKRN1-895H Recombinant Human MKRN1, GST-tagged E.coli GST N-term-349aa
Human MKRN1-4300HCL Recombinant Human MKRN1 293 Cell Lysate HEK293 N/A
Human MKRN1-022H Recombinant Human MKRN1 Protein, Flag-tagged HEK293 Flag
Human MKRN1-6343HF Recombinant Full Length Human MKRN1 Protein, GST-tagged In Vitro Cell Free System GST 482 amino acids
Human MKRN1-5372H Recombinant Human MKRN1 Protein, GST-tagged Wheat Germ GST
Human MKRN1-3380H Recombinant Human MKRN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Mkrn1-4085M Recombinant Mouse Mkrn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish MKRN1-9444Z Recombinant Zebrafish MKRN1 Mammalian Cell His
Chicken MKRN1-6307C Recombinant Chicken MKRN1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MKRN1 involved in several pathways and played different roles in them. We selected most pathways MKRN1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MKRN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemASB3;KIR2DS2;SEC23A;UBR1;WWP1;KIF2A;RACGAP1;ASB14;ASB7
Antigen processing: Ubiquitination &ampCMTM2A;ATG7;TRIM9;ASB11;ASB7;UBE2F;ASB6;RNF14;LRRC41
Proteasome degradationHECTD3;ARIH2;ASB13;ASB18;UBE2J2;MKRN1;UBE2V2;TRIM69;KLHL20
Class I MHC mediated antigen processing &ampUBE2U;UBR1;RNF34;SEC24A;RNF220;RNF14;ASB10;TPP2;UBE2E3
presentationGAN;FBXO27;CTSS;B2ML;RNF123;CTSL2;VPRBP;RNF41;PJA2
Immune SystemUBE2E3;KLHL21;IgG3;SEC23A;FCGR1B;CD300LB;CRP;NCKAP1;FCN2

MKRN1 has several biochemical functions, for example, chromatin binding, ligase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKRN1 itself. We selected most functions MKRN1 had, and list some proteins which have the same functions with MKRN1. You can find most of the proteins on our site.

Function Related Protein
chromatin bindingHMGA1;MAZ;NCOA5;KDM5A;SSBP1;BRD4;HOXD13;TADA2B;UXT
ligase activityPELI3;RNF40;UBE2KB;ATG3;MARCH8;RFWD3;RNF213;UBE2L3A;HUWE1
poly(A) RNA bindingCAPRIN1;KTN1;VCP;RBM15B;CPSF6;ACTN4;RPL26L1;RPL5;SMC1A
protein bindingEFNA4;GDI1;HOXA9;ITGB1;ANKRD45;PRPF6;RAB27A;FLOT1;PIP5K1C
ubiquitin-protein transferase activityWWP2;CDC34;BIRC5A;RNF151;FBXO21;AMFR;FBXL14B;UBE2E3;FBXO11
zinc ion bindingATRX;MMP24;ZCCHC6;RYBPB;ADAM9;FBXO40.1;GRIN2A;TRIM35-30;SEC23B

MKRN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKRN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MKRN1.

TP53; CDKN1A; UBC; UBE2D3; ctc; X; UBE2W; EXOSC8; DUSP23

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