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Official Full Name makorin ring finger protein 1
Background The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of;intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the;MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000 (PubMed 10843807)).
Synonyms MKRN1; makorin ring finger protein 1; E3 ubiquitin-protein ligase makorin-1; RNF61; RING finger protein 61; FLJ21334
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Flag
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MKRN1-022H Recombinant Human MKRN1 Protein, Flag-tagged HEK293 Flag
    Human MKRN1-3380H Recombinant Human MKRN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Mkrn1-4085M Recombinant Mouse Mkrn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MKRN1-4300HCL Recombinant Human MKRN1 293 Cell Lysate HEK293 N/A
    Human MKRN1-5372H Recombinant Human MKRN1 Protein, GST-tagged Wheat Germ GST
    Human MKRN1-895H Recombinant Human MKRN1, GST-tagged E.coli GST
    Chicken MKRN1-6307C Recombinant Chicken MKRN1 Mammalian Cell His
    Zebrafish MKRN1-9444Z Recombinant Zebrafish MKRN1 Mammalian Cell His

    MKRN1 involved in several pathways and played different roles in them. We selected most pathways MKRN1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MKRN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System GAN; CLEC2D; LILRB2; CREB1; NCR3LG1; PTBP3; FGF20A; LRR1; CREB1B; EVL
    Antigen processing: Ubiquitination &amp RBCK1; RNF14; TRIM41; TRIM63; ASB11; LRSAM1; ATG7; GAN; TPP2; RNF34
    Proteasome degradation ASB6; ASB14; KLHL21; TRIM69; ASB11; ASB8; UBE2F; RNF111; LRSAM1; TRIM11
    Class I MHC mediated antigen processing &amp RNF19B; UBE2V1; LRR1; UFL1; STUB1; LTN1; ASB17; B2ML; TRIM69; TRIM63
    presentation ASB13; KLHL21; ASB3; UBE2U; TRIM63; TRIM39; ARIH2; ASB18; SH3RF1; RNF123
    Immune System SH2D1B; SIGLEC11; DYNC1I2; PELI3; IFI6; GRAP2B; LRSAM1; TRIM63; HBL3; MB21D1

    MKRN1 has several biochemical functions, for example, chromatin binding, ligase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKRN1 itself. We selected most functions MKRN1 had, and list some proteins which have the same functions with MKRN1. You can find most of the proteins on our site.

    Function Related Protein
    chromatin binding ATXN7; LDB2A; YBX1; NCAPD3; SIRT2; NIPBL; MBD1; TCF3; MLH3; MEF2A
    ligase activity PET112L; RFWD3; MARCH9; UNKL; TRIML1; RNF144B; SHPRH; TTLL4; TRIM8; RANBP2
    poly(A) RNA binding RBM38; RSL24D1; RPLP0; FLNA; RPL19; DUS3L; FLYWCH2; HMGN2; TPT1; CLNS1A
    protein binding CLK1; SERPINA3K; ADCK3; TRPC6; CRP; TGIF2LY; RUVBL2; PGM2; SELP; PINX1
    ubiquitin-protein transferase activity UBR1; RBCK1; MARCH2; UBE2W; HECW2; PDZRN3B; NLRC4; RNF181; TOPORS; BRAP
    zinc ion binding MYLIP; GALT; DPYS; MICAL1; MAN2B2; WTIP; TRAF1; NR1H3; BIRC7; RNF31

    MKRN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKRN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MKRN1.

    TP53; CDKN1A; UBC; UBE2D3; ctc; X; UBE2W; EXOSC8; DUSP23

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