Recombinant Human MKRN1 Protein, Flag-tagged


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Recombinant Human MKRN1 Protein, Flag-tagged

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Cat.No. : MKRN1-022H
Product Overview : Recombinant Human MKRN1 Protein (transcript variant 1) is produced by HEK293T expression system. This protein is fused with a Flag tag.
Description : This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293
Species : Human
Tag : Flag
Form : PBS buffer
Molecular Mass : 53 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Gene Name : MKRN1 makorin ring finger protein 1 [ Homo sapiens ]
Official Symbol : MKRN1
Synonyms : MKRN1; makorin ring finger protein 1; FLJ21334;
Gene ID : 23608
mRNA Refseq : NM_001145125
Protein Refseq : NP_001138597
MIM : 607754
UniProt ID : Q9UHC7
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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