mmp16
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  • Official Full Name
  • matrix metallopeptidase 16 (membrane-inserted)
  • Background
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]
  • Synonyms
  • MMP16; matrix metallopeptidase 16 (membrane-inserted); MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP; matrix metalloproteinase-16; MMP-16; MT3MMP; MTMMP3; MT-MMP 3; Putative transmembrane protein C8orf57; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase;
Cat.#:MMP16-608HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP16, Catalytic Domain
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Cat.#:MMP16-7089HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP16 protein, His & T7-tagged
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Cat.#:MMP16-3714RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MMP16 Protein
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Cat.#:MMP16-6751CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MMP16
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Involved Pathway

MMP16 involved in several pathways and played different roles in them. We selected most pathways MMP16 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MicroRNAs in cancer
HMOX1; RAF1; TNN; STMN1; TNR; ABCB1A; ABCB1; MARCKS; HDAC4; WNT3

Protein Function

MMP16 has several biochemical functions, for example, calcium ion binding, enzyme activator activity, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP16 itself. We selected most functions MMP16 had, and list some proteins which have the same functions with MMP16. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein VLDLR; SYT2; SYT16; SMOC2; PCDH2AA15; PLCD1A; DSC2; SMOC1; EFCAB2; DSG2.1
Function enzyme activator activity
Related Protein GMFB; TAB1; CLPSL1; PPP1R12B; CTSA; SFTPB; LTC4S; SLX4; ASAP2; CLPS
Function metalloendopeptidase activity
Related Protein MMP8; ADAMTS1; MMP24; PMPCB; PAPPAA; ADAM23; ADAM8; C6AST1; ADAMTS15A; YME1L1
Function zinc ion binding
Related Protein MMP23B; ADAM18; UPF1; TRIM24; CIZ1B; PPARD; ZDHHC20; TP53I3; ADAMTS5; HDAC4

Interacting Protein

MMP16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP16.
Gorasp2

MMP16 Related Gene Family

MMPs