mrpl2
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  • Official Full Name
  • mitochondrial ribosomal protein L2
  • Background
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q.
  • Synonyms
  • MRPL2; mitochondrial ribosomal protein L2; 39S ribosomal protein L2, mitochondrial; CGI 22; MRP L14; RPML14; 39S ribosomal protein L2, mitochondrial precursor; CGI22; MRPL14; L2mt; MRP-L2; CGI-22; MRP-L14
Cat.#:MRPL2-5564HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MRPL2 Protein, GST-tagged
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Cat.#:MRPL2-681HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human mitochondrial ribosomal protein L2, His-tagged
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Cat.#:MRPL2-987HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MRPL2, GST-tagged
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Cat.#:Mrpl2-1398MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mrpl2 protein, His & T7-tagged
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Cat.#:MRPL2-3766RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MRPL2 Protein
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Cat.#:MRPL2-4190HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MRPL2 293 Cell Lysate
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Involved Pathway

MRPL2 involved in several pathways and played different roles in them. We selected most pathways MRPL2 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome
RPL9; RPL12; MRPL33; RPS8A; RPL35A; RPLP2L; RPS19; MRPS9; MRPL2; RPL5A

Protein Function

MRPL2 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL2 itself. We selected most functions MRPL2 had, and list some proteins which have the same functions with MRPL2. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein TPT1; SECISBP2; VCP; ATP5C1; NXF1; FXR2; SBDS; RPP25L; MOV10; RBM42
Function structural constituent of ribosome
Related Protein DAP3; RPS28; RPS3A; RPS8B; MRPL33; RPL36; RPL5; RPL14; RPL7A; RPL17
Function transferase activity
Related Protein EOGT; GAL3ST3; ST6GALNAC5B; GBGT1L3; CSNK1DA; UGT5C1; MGAT3A; BMPR1AB; TAOK1; ZDHHC8B

Interacting Protein

MRPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL2.
CMTM4; TRIM63; SMURF2; Brwd3; Ncstn; YBX1; ICT1; EZH2; MRPL50; MASTL; MRPL9; MRPL1

MRPL2 Related Articles

van der Giezen, M; Birdsey, GM; et al. Fungal hydrogenosomes contain mitochondrial heat-shock proteins. MOLECULAR BIOLOGY AND EVOLUTION 20:1051-1061(2003).