mrpl42
Share
  • Official Full Name
  • mitochondrial ribosomal protein L42
  • Background
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
  • Synonyms
  • MRPL42; mitochondrial ribosomal protein L42; 39S ribosomal protein L42, mitochondrial; HSPC204; MRP L31; MRPL31; MRPS32; PTD007; RPML31; mitochondrial; 28S ribosomal protein S32; 39S ribosomal protein L31; 39S ribosomal protein L42; L31mt; L42mt; Mitochondrial ribosomal protein S32; MRP L42; MRP S32; MRP-L31; MRP-L42; MRP-S32; RM42_HUMAN; S32mt; 28S ribosomal protein S32, mitochondrial; 39S ribosomal protein L31, mitochondrial
Cat.#:MRPL42-10069MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MRPL42 Protein
+Inquiry
Cat.#:MRPL42-4167HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MRPL42 293 Cell Lysate
+Inquiry

Involved Pathway

MRPL42 involved in several pathways and played different roles in them. We selected most pathways MRPL42 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Mitochondrial translation
MRPL10; MRPL45; MRPL49; MRPL41; MRPS36; CHCHD1; MRPL52; MRRF; MRPS27; MRPS30
Mitochondrial translation elongation
MRPS31; MRPL52; MRPL51; ICT1; MRPL48; MRPL3; MRPS23; CHCHD1; MRPL41; MRPL10
Mitochondrial translation initiation
MRPS25; MRPL41; MRPL49; MRPL48; MRPL3; MRPS26; MRPL28; MRPS23; MRPL55; MRPL38
Mitochondrial translation termination
MRPL39; MRPL41; MRPL52; MRPL44; GFM2; MRPL48; MRPL38; MRPS30; MRPS28; MRPL53
Organelle biogenesis and maintenance
TTC30A2; IFT46; LZTFL1; EXOC3; PTCD3; DYNLRB1; MRPL53; IQCB1; TTC30A1; RABL5

Protein Function

MRPL42 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL42 itself. We selected most functions MRPL42 had, and list some proteins which have the same functions with MRPL42. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein RPS25; ZFML; RPS4X; FAM98C; NVL; RPS24; GTF2F1; PABPN1; PPIL4; HSPA9
Function structural constituent of ribosome
Related Protein RPS19; RPL31; RPL7A; MRPL35; RPS9; MRPS9; RPS5; RPL18A; RPSA; MRPS6

Interacting Protein

MRPL42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL42 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL42.
rev; IKBKAP; EEF1A1