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MRPL50

Official Full Name

mitochondrial ribosomal protein L50
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.
Synonyms

MRPL50; mitochondrial ribosomal protein L50; 39S ribosomal protein L50, mitochondrial; FLJ20493; mitochondrial 39S ribosomal protein L50; MRP L50; L50mt; MRP-L50;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPL50-1097H	Recombinant Human MRPL50	Mammalian Cell	His		Inquiry
Human	MRPL50-4159HCL	Recombinant Human MRPL50 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MRPL50-5594H	Recombinant Human MRPL50 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPL50-3520H-B	Recombinant Human MRPL50 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	MRPL50-6440HF	Recombinant Full Length Human MRPL50 Protein, GST-tagged	In Vitro Cell Free System	GST	158 amino acids	Inquiry
Human	MRPL50-3520H	Recombinant Human MRPL50 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	MRPL50-2849R	Recombinant Rhesus monkey MRPL50 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	MRPL50-2669R	Recombinant Rhesus Macaque MRPL50 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	MRPL50-2669R-B	Recombinant Rhesus Macaque MRPL50 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	MRPL50-1720C	Recombinant Chicken MRPL50	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MRPL50 involved in several pathways and played different roles in them. We selected most pathways MRPL50 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPS27;AURKAIP1;MRPS30;MRPS36;MRPS35;MTRF1L;MRPL41;MRPL40;MRPL48
Mitochondrial translation elongation	MRPS35;MRPL39;MRPS34;ICT1;MRPL10;MRPS30;DAP3;MRPL50;MRPS26
Mitochondrial translation initiation	MRPL51;MRPS36;MTIF3;MRPS27;MRPS26;MRPS25;MRPL38;CHCHD1;MTFMT
Mitochondrial translation termination	MRPL38;MRPL52;MRPL50;MRPL28;GADD45GIP1;MRRF;MTRF1L;MRPS25;MRPL53
Organelle biogenesis and maintenance	IFT22;BBS10;DYF-1;IFT172;TTC30B;RABL5;IFT27;MRPS24;MRPL3

MRPL50 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL50 itself. We selected most functions MRPL50 had, and list some proteins which have the same functions with MRPL50. You can find most of the proteins on our site.

Function	Related Protein

MRPL50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL50 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL50.

MRPL43; b4dln1_human; MRPL27; ATP5J2-PTCD1; MRPL42; ICT1; MRPL4; XRCC2; SYNCRIP; MRPL33; PCF11; TBC1D8; TRUB2; MRPL3; MRPL19; MRPL12; CORO7; MRPS35; MRPS6; HNRNPU