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MTA2

  • Official Full Name

    metastasis associated 1 family, member 2

  • Overview

    MTA1 (metastasis associated gene 1) was identified in a differential screening of a cDNA library of metastatic and nonmetastatic adenocarcinoma cell lines (1), and was subsequently found to be an integral member of the nucleosome remodeling and deacetylat
  • Synonyms

    MTA2; metastasis associated 1 family, member 2; metastasis associated gene family, member 2 , MTA1L1; metastasis-associated protein MTA2; MTA1 L1; MTA1-L1 protein; metastasis-associated 1-like 1; metastasis-associated protein 2; metastasis -associated gen;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MTA2-26H Recombinant Human MTA2 protein, GST-tagged Wheat Germ GST
Human MTA2-1071H Recombinant Human MTA2, GST-tagged E.coli GST 1-350aa
Human MTA2-294H Recombinant Human MTA2 Protein, His-tagged E.coli His Met1~Cys394
Human MTA2-5298H Recombinant Human MTA2 Protein (Met1-Cys394), N-His tagged E.coli N-His Met1-Cys394
Mouse MTA2-10162M Recombinant Mouse MTA2 Protein Mammalian Cell His
Mouse MTA2-5763M Recombinant Mouse MTA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MTA2-5763M-B Recombinant Mouse MTA2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MTA2-2890R Recombinant Rhesus monkey MTA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MTA2-2710R Recombinant Rhesus Macaque MTA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MTA2-2710R-B Recombinant Rhesus Macaque MTA2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MTA2-12725Z Recombinant Zebrafish MTA2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MTA2 involved in several pathways and played different roles in them. We selected most pathways MTA2 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesSAP30L;DPY30;KAT7A;GATAD2A;SMYD2A;KAT6A;CAPNS2;SUZ12A;MSL2B
Chromatin organizationKAT7A;PAX3A;EP400;DPY30;ARID1A;ING5A;SAP30L;KANSL3;PRMT7
EGFR1 Signaling PathwayZPR1;SPRY2;ZNF259;RALBP1;TNK2;MTA2;ARF4;RBB4L;CEACAM1
Gene ExpressionYAP1;KIAA1456;IGF2BP1;EIF2S1;EIF2C3;HENMT1;ZFP1;NR0B2A;FAUB
HDACs deacetylate histonesARID4A;HMG20B;MBD3;MTA3;ANO9A;KDM1A;MTA2;MBD3A;PHF21A
RNA Polymerase I Promoter ClearanceRRN3;TAF1A;EFCAB11;GATAD2A;CHD4A;UBTF;MTA2;CHD4;GATAD2B
RNA Polymerase I TranscriptionMBD3B;MTA3;CHD4;GATAD2A;CBX3;MTA1;GATAD2B;TAF1A;MBD3A
RNA Polymerase I Transcription InitiationMTA1;MBD3A;MTA3;MTA2;RRN3;CHD4A;MBD3;GATAD2A;MBD3B

MTA2 has several biochemical functions, for example, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding, contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II repressing transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTA2 itself. We selected most functions MTA2 had, and list some proteins which have the same functions with MTA2. You can find most of the proteins on our site.

Function Related Protein
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA bindingACTL6A;RBBP4;ACTB;SMARCA4;SMARCC2;MTA2;SMARCC1;SMARCE1;HDAC1
contributes_to RNA polymerase II distal enhancer sequence-specific DNA bindingSMARCC1;SMARCE1;MTA2;SMARCA4;SMARCB1;RBBP4;MBD3;SMARCC2;HDAC1
RNA polymerase II repressing transcription factor bindingGATA6;DMAP1;RBBP8;SIN3A;BBS2;BBS4;MTA1;TBX5A;HDAC2
RNA polymerase II transcription factor bindingPITX2;GATA4;TBX3;TRP53;SPI1;ATF4;TRPS1;GSC;TAL1
histone deacetylase activitySIRT1;HDAC7;HDAC9B;HDAC11;HDAC4;HDAC2;HDAC6;HDAC1;SIRT2
contributes_to nucleosomal DNA bindingSMARCB1;RBBP4;MBD3;GATAD2B;MTA2;ACTB;SMARCE1;HDAC2;SMARCC2
protein bindingPLAT;VPS36;COX6B2;SBDS;TDGF1;STRADA;CALML3;UBE2K;KIF18B
transcription factor activity, sequence-specific DNA bindingZNF549;NPAS2;GAS7;MNX1;TFAP2C;ZNF193;FOXD3;HIF1AB;NR1D2B
transcription factor activity, transcription factor bindingFOXO1;CRY1;PER1;CRY2;LDB2A;TRP63;ASCL1A;LDB1A;ASCL1B
zinc ion bindingZNF385D;VPS8;MMP24;MYLIPA;MTA3;C11orf54;GRIN2B;ERAP2;TRAF4A

MTA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTA2.

HDAC1; HDAC2; MBD3; PARK7

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