MUC5AC
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Official Full Name
Mucin 5AC, Oligomeric Mucus/Gel-Forming
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Overview
Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. -
Synonyms
MUC5AC; mucin 5AC, oligomeric mucus/gel-forming; TBM; leB; MUC5; mucin-5AC; gastric mucin; tracheobronchial mucin; major airway glycoprotein; lewis B blood group antigen; mucin-5 subtype AC, tracheobronchial; mucin 5, subtypes A and C, tracheobronchial/gastric;
- Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Mammalian cells
- Wheat Germ
- C
- Fc
- GST
- His
- His|GST
- His|T7
- Myc
- DDK
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | MUC5AC-28542TH | Recombinant Human MUC5AC protein, GST-tagged | Wheat Germ | GST | ||
Human | MUC5AC-16H | Recombinant Human MUC5AC protein, His-tagged | E.coli | His | ||
Human | MUC5AC-12HFL | Recombinant Full length Human MUC5AC Protein, C-MYC/DDK-tagged | HEK293 | Myc-DDK | ||
Human | MUC5AC-17H | Recombinant Human MUC5AC Protein, His-tagged | E.coli | His | Tyr5568~His5654 | |
Human | MUC5AC-4630H | Recombinant Human MUC5AC Protein (Asn5528-His5627), C-Fc tagged | Mammalian cells | C-Fc | Asn5528-His5627 | |
Mouse | Muc5ac-7624M | Recombinant Mouse Muc5ac protein, His-tagged | E.coli | His | Val2040~Tyr2149 (Accession # E9PWB6) | |
Mouse | Muc5ac-7626M | Recombinant Mouse Muc5ac protein, His & GST-tagged | E.coli | His/GST | Val2040~Tyr2149 (Accession # E9PWB6) | |
Mouse | Muc5ac-7625M | Recombinant Mouse Muc5ac protein, His-tagged | E.coli | His | Gly430~Pro549 (Accession # E9PWB6) | |
Mouse | Muc5ac-5313M | Recombinant Mouse Muc5ac protein, His-tagged | E.coli | His | 2452-2721aa | |
Rat | Muc5ac-7627R | Recombinant Rat Muc5ac protein, His-tagged | E.coli | His | Met2662~Gln2755 | |
Rat | Muc5ac-7628R | Recombinant Rat Muc5ac protein, His & T7-tagged | E.coli | His/T7 | Val324~Gln406 |
- Involved Pathway
- Protein Function
- Interacting Protein
- MUC5AC Related Articles
MUC5AC involved in several pathways and played different roles in them. We selected most pathways MUC5AC participated on our site, such as Metabolism of proteins, O-linked glycosylation, O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC5AC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolism of proteins | LTF;TOMM7;SENP5;KDELR3;ARSD;PPP6R3;TIMM17B;SEC63;MAN1B1 |
O-linked glycosylation | ADAMTSL1;GALNTL2;ADAMTS15;GALNT13;GALNT5;B3GNT8;MUC5AC;B3GALTL;GALNTL5 |
O-linked glycosylation of mucins | GALNT6;GALNTL2;ST6GALNAC2;GALNTL5;GALNT13;MUCL1;KCNA6;A4GNT;GALNT5 |
Post-translational protein modification | PROZ;MAN1A2;TRAPPC1;ADAMTS3;PREB;MCFD2;DPAGT1;ADAMTS5;ADAMTSL1 |
Termination of O-glycan biosynthesis | MUC20;MUC12;MUC21;MUC13;MUC1;MUC4;MUCL1;MUC5AC;MUC15 |
MUC5AC has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by MUC5AC itself. We selected most functions MUC5AC had, and list some proteins which have the same functions with MUC5AC. You can find most of the proteins on our site.
Function | Related Protein |
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extracellular matrix structural constituent | ELNA;LUM;FBLN2;COL2A1B;IMPG2;COL4A6;COL1A1A;PXDN;COL5A3B |
MUC5AC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC5AC here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC5AC.
MYC
- Q&As
- Reviews
Q&As (7)
Ask a questionMUC5AC is produced by goblet cells in the airway epithelium and is mainly found in mucus lining the respiratory tract.
Dysregulated or elevated expression of MUC5AC is often observed in respiratory conditions such as asthma, chronic bronchitis, and cystic fibrosis.
Mucin 5AC (MUC5AC) primarily functions in the respiratory system by providing protection and lubrication to the airway epithelium.
Abnormal MUC5AC expression in lung diseases can contribute to mucus hypersecretion, airway obstruction, and impaired respiratory function.
Regulation of MUC5AC expression involves specific signaling pathways and molecular mechanisms, including the activation of transcription factors in response to inflammatory stimuli.
MUC5AC plays a crucial role in the defense against foreign particles and microorganisms by trapping and eliminating them from the respiratory tract.
In protecting and lubricating the epithelium, MUC5AC helps prevent foreign particles and microorganisms from adhering to the airway surfaces.
Customer Reviews (3)
Write a reviewPositive feedback from other labs and researchers confirmed its standing as a valuable research tool.
The product's innovative features hinted at its potential for advancing our research in uncharted territories.
Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.
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