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MUC5AC

  • Official Full Name

    Mucin 5AC, Oligomeric Mucus/Gel-Forming

  • Overview

    Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene.
  • Synonyms

    MUC5AC; mucin 5AC, oligomeric mucus/gel-forming; TBM; leB; MUC5; mucin-5AC; gastric mucin; tracheobronchial mucin; major airway glycoprotein; lewis B blood group antigen; mucin-5 subtype AC, tracheobronchial; mucin 5, subtypes A and C, tracheobronchial/gastric;

  • Recombinant Proteins
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • GST
  • His
  • His|GST
  • His|T7
  • Myc
  • DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MUC5AC-28542TH Recombinant Human MUC5AC protein, GST-tagged Wheat Germ GST
Human MUC5AC-16H Recombinant Human MUC5AC protein, His-tagged E.coli His
Human MUC5AC-12HFL Recombinant Full length Human MUC5AC Protein, C-MYC/DDK-tagged HEK293 Myc-DDK
Human MUC5AC-17H Recombinant Human MUC5AC Protein, His-tagged E.coli His Tyr5568~His5654
Human MUC5AC-4630H Recombinant Human MUC5AC Protein (Asn5528-His5627), C-Fc tagged Mammalian cells C-Fc Asn5528-His5627
Mouse Muc5ac-7624M Recombinant Mouse Muc5ac protein, His-tagged E.coli His Val2040~Tyr2149 (Accession # E9PWB6)
Mouse Muc5ac-7626M Recombinant Mouse Muc5ac protein, His & GST-tagged E.coli His/GST Val2040~Tyr2149 (Accession # E9PWB6)
Mouse Muc5ac-7625M Recombinant Mouse Muc5ac protein, His-tagged E.coli His Gly430~Pro549 (Accession # E9PWB6)
Mouse Muc5ac-5313M Recombinant Mouse Muc5ac protein, His-tagged E.coli His 2452-2721aa
Rat Muc5ac-7627R Recombinant Rat Muc5ac protein, His-tagged E.coli His Met2662~Gln2755
Rat Muc5ac-7628R Recombinant Rat Muc5ac protein, His & T7-tagged E.coli His/T7 Val324~Gln406
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MUC5AC Related Articles

MUC5AC involved in several pathways and played different roles in them. We selected most pathways MUC5AC participated on our site, such as Metabolism of proteins, O-linked glycosylation, O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC5AC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsLTF;TOMM7;SENP5;KDELR3;ARSD;PPP6R3;TIMM17B;SEC63;MAN1B1
O-linked glycosylationADAMTSL1;GALNTL2;ADAMTS15;GALNT13;GALNT5;B3GNT8;MUC5AC;B3GALTL;GALNTL5
O-linked glycosylation of mucinsGALNT6;GALNTL2;ST6GALNAC2;GALNTL5;GALNT13;MUCL1;KCNA6;A4GNT;GALNT5
Post-translational protein modificationPROZ;MAN1A2;TRAPPC1;ADAMTS3;PREB;MCFD2;DPAGT1;ADAMTS5;ADAMTSL1
Termination of O-glycan biosynthesisMUC20;MUC12;MUC21;MUC13;MUC1;MUC4;MUCL1;MUC5AC;MUC15

MUC5AC has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by MUC5AC itself. We selected most functions MUC5AC had, and list some proteins which have the same functions with MUC5AC. You can find most of the proteins on our site.

Function Related Protein
extracellular matrix structural constituentELNA;LUM;FBLN2;COL2A1B;IMPG2;COL4A6;COL1A1A;PXDN;COL5A3B

MUC5AC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC5AC here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC5AC.

MYC

Vo, DTN; Nakayama, T; et al. Progression risk assessments of individual non-invasive gastric neoplasms by genomic copy-number profile and mucin phenotype. BMC MEDICAL GENOMICS 8:-(2015).
Cserni, G; et al. Reversed polarity of the glandular epithelial cells in micropapillary carcinoma of the large intestine and the EMA/MUC1 immunostain. PATHOLOGY 46:527-532(2014).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
How is MUC5AC produced and where is it mainly found in the body? 05/22/2022

MUC5AC is produced by goblet cells in the airway epithelium and is mainly found in mucus lining the respiratory tract.

In which respiratory conditions is MUC5AC expression often dysregulated or elevated? 06/25/2020

Dysregulated or elevated expression of MUC5AC is often observed in respiratory conditions such as asthma, chronic bronchitis, and cystic fibrosis.

What is the primary role of mucin 5AC (MUC5AC) in the respiratory system? 04/01/2019

Mucin 5AC (MUC5AC) primarily functions in the respiratory system by providing protection and lubrication to the airway epithelium.

What are the implications of abnormal MUC5AC expression in lung diseases? 01/16/2019

Abnormal MUC5AC expression in lung diseases can contribute to mucus hypersecretion, airway obstruction, and impaired respiratory function.

Are there specific signaling pathways or molecular mechanisms associated with the regulation of MUC5AC expression? 07/17/2018

Regulation of MUC5AC expression involves specific signaling pathways and molecular mechanisms, including the activation of transcription factors in response to inflammatory stimuli.

How does MUC5AC contribute to the defense against foreign particles and microorganisms in the respiratory tract? 06/27/2017

MUC5AC plays a crucial role in the defense against foreign particles and microorganisms by trapping and eliminating them from the respiratory tract.

What functions does MUC5AC serve in protecting and lubricating the epithelium of the airways? 07/24/2016

In protecting and lubricating the epithelium, MUC5AC helps prevent foreign particles and microorganisms from adhering to the airway surfaces.

Customer Reviews (3)

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Reviews
03/03/2022

    Positive feedback from other labs and researchers confirmed its standing as a valuable research tool.

    07/10/2018

      The product's innovative features hinted at its potential for advancing our research in uncharted territories.

      01/28/2018

        Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

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