myo5a
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  • Official Full Name
  • myosin VA (heavy chain 12, myoxin)
  • Background
  • This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of;actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA;translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene;cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or;Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported,;but the full-length nature of some variants has not been determined.
  • Synonyms
  • MYO5A; myosin VA (heavy chain 12, myoxin); MYH12, myosin VA (heavy polypeptide 12, myoxin); unconventional myosin-Va; GS1; MYO5; myosin heavy chain 12; myosin V; myosin; heavy polypeptide kinase; myoxin; MYR12; myosin-12; myosin-Va; myosin, heavy polypep
Cat.#:MYO5A-5841HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MYO5A Protein, GST-tagged
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Cat.#:MYO5A-8026HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYO5A protein, His & T7-tagged
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Cat.#:MYO5A-10340MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MYO5A Protein
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Cat.#:MYO5A-3866RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MYO5A Protein
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Cat.#:MYO5A-6852CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MYO5A
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Protein Function

MYO5A has several biochemical functions, for example, ATP binding, ATP-dependent protein binding, Rab GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYO5A itself. We selected most functions MYO5A had, and list some proteins which have the same functions with MYO5A. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PARS2; HIPK3B; MYO1G; IP6K1; TTL; NADK; NTRK2; GNE; CAMKK1B; RIPK1
Function ATP-dependent protein binding
Related Protein DDX39B; PRNP; DNAJC5; MYO5A; SAE1; STX1A
Function Rab GTPase binding
Related Protein Fert2; EXPH5; ANKRD27; ODF2; AP3M1; RILP; RUSC2; RABGGTB; RAB11FIP5; HACE1
Function SNARE binding
Related Protein STX2A; EXOC3L4; STX5A; STX3A; VAMP1; STX4A; GABARAPL2; VAMP5; STX1A; ANKRD27
Function actin binding
Related Protein DIXDC1; FSCN2B; EMD; CALD1; KCNMA1; EPB41L3A; LSP1; GMFG; TPMA; DIAPH1
Function calcium ion binding
Related Protein ANXA11A; C2CD4A; ANXA3A; EFHC2; MYL9B; NCS1B; CLSTN3; HEG; PPP3CA; ACTN1
Function calcium-dependent protein binding
Related Protein ANXA3; TSG101; PDCD6IP; SELP; SYT8; MYO1D; NRXN1; CLEC4M; MASP1; PLSCR3
Function calmodulin binding
Related Protein CAMK2G; PCP4; MYO1D; MYO1C; RGS4; RYR1; ITPKB; MYO1F; ARPP21; KCNH1
Function microfilament motor activity
Related Protein MYO1D; MYO3A; MYH7; MYO7A; MYH3; STRC; MYO5B; MYO1E; MYH13; MYO9B
Function motor activity
Related Protein SMYHC3; MYH6; DYNC2H1; DCTN1; DNAL4; DYNLL2; MYO1G; KIF1C; DYNC2LI1; MYO1A
Function nucleotide binding
Related Protein RAF1A; SF3B4; GM4922; CAMKK1A; GDPGP1; MAPK12B; SMOK2B; RBMS3; RASL11A; ABCB6A
Function poly(A) RNA binding
Related Protein HSD17B10; NXF3; UCHL5; ZFP346; EEF2; TRIM56; DDX39B; ISG20L2; PTCD3; RPL14
Function protein binding
Related Protein ARHGEF12; CKM; SERTAD1; AKR1C1; RNF10; C20orf195; RC3H2; MED17; HNRNPH3; LANCL2
Function protein dimerization activity
Related Protein HES3; PIP; TFEC; MEF2CB; EBF3A; MYCS; ATOH7; ID2; CLOCK; MEF2AA
Function protein heterodimerization activity
Related Protein ZHX3; CLNS1A; LIFR; HIST1H2BA; TCF4; SYT5; HIST1H2BK; ADRA2C; HIST1H2BD; IKZF3
Function syntaxin-1 binding
Related Protein SYT1; MYO5A; SNPH; UNC13A; LRRK2; STXBP3A; VAMP2; DAPK1; SNAP25B; NSF

Interacting Protein

MYO5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYO5A here. Most of them are supplied by our site. Hope this information will be useful for your research of MYO5A.
Grin1; Grin2b; Slc17a9; Nos1; NPHP4; Csf1; SNCA; Hmga2; Ywhae; Ywhab