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Recombinant Human MYO5A protein, His & T7-tagged

Cat.No. : MYO5A-8026H
Product Overview : Recombinant Human MYO5A aa. (Ser1531~Val1855 (Accession # Q9Y4I1)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 40.9kDa
Protein length : Ser1531~Val1855 (Accession # Q9Y4I1)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 8.6.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : MYO5A myosin VA [ Homo sapiens (human) ]
Official Symbol : MYO5A
Synonyms : MYO5A; myosin VA; GS1; MYO5; MYH12; MYR12; unconventional myosin-Va; dilute myosin heavy chain, non-muscle; myosin V; myosin VA (heavy chain 12, myoxin); myosin, heavy polypeptide kinase; myosin-12; myosin-Va; myoxin
Gene ID : 4644
mRNA Refseq : NM_000259.3
Protein Refseq : NP_000250.3
UniProt ID : Q9Y4I1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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