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Official Full Name nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Background The NFAT (nuclear factor of activated T cells) family of proteins consists of NFAT1 (NFATc2 or NFATp), NFAT2 (NFATc1 or NFATc), NFAT3 (NFATc4), and NFAT4 (NFATc3 or NFATx). All members of this family are transcription factors with a Rel homology domain an
Synonyms NFATC3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; nuclear factor of activated T-cells, cytoplasmic 3; NFAT4; NFATX; NF-ATc3; T cell transcription factor NFAT4; nuclear factor of activated T-cells c3 isoform IE-Xa
    • Species :
    • Human
    • Source :
    • HEK293
    • Wheat Germ
    • Tag :
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NFATC3-236H Recombinant Human NFATC3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human NFATC3-27538TH Recombinant Human NFATC3 Wheat Germ N/A
    Human NFATC3-29252TH Recombinant Human NFATC3 Wheat Germ N/A
    Human NFATC3-3856HCL Recombinant Human NFATC3 293 Cell Lysate HEK293 N/A

    NFATC3 involved in several pathways and played different roles in them. We selected most pathways NFATC3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFATC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway GNAI2; ROCK2; IRS2; CALM1; GNAI1; PPP1CB; CREB3L1; PLCB2; AKT1; MYLK4
    Wnt signaling pathway MAPK8; CXXC4; DKK4; DVL1B; MAPK10; CCND1; SIAH1; CAMK2A; RAC3; FZD9
    Axon guidance EPHA4A; GSK3B; MARK3; KRAS; PLXNB2; TRPC5; KALRNB; CD24; TRPC3; SEMA4C
    T cell receptor signaling pathway NFKBIB; GRAP2; NCK2; PLCG1; CD3E; CD3D; PAK1; GRB2; GSK3B; CD3D; MAP2K2
    B cell receptor signaling pathway ACTR2; ACTR3; RELA; TTC6; DUSP4; PLCG2; PIK3CD; NFKBIE; CARD11; LAT2
    Oxytocin signaling pathway PIK3R3; GNAI3; NPR1; PLA2G4F; CAMK1G; PPP3CC; CAMK4; EEF2K; PLA2G4C; PPP1R12C
    Hepatitis B EGR3; IFN-a; IFNA2; BAX; CXCL8; IFNA5; TGFBR1; TRP53; MYD88; STAT2
    HTLV-I infection SLC25A6; CD3E; CD3D; TP53; WNT9B; HLA-DRB1; ATF1; NFKB2; TSPO; IL6; ITGB2L

    NFATC3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by NFATC3 itself. We selected most functions NFATC3 had, and list some proteins which have the same functions with NFATC3. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter proximal region sequence-specific DNA binding CLOCK; SIX4; TFAM; ZIC1; KCNIP3; CREB3L2; EP300; HHEX; ALS2CR8; GABPA
    chromatin binding UBE2T; HMGB2; NONO; CHD7; TRP53; HDGF2; RELA; SOX9A; ATOH1A; ZFP143
    protein binding CST2; EXOSC4; DHH; PBK; SEC14L4; PPP2CB; EIF3F; IPO7; COX4I1; SYMPK
    transcription factor binding GTF2B; E2F2; RBFOX2; HES2; SRY; MAPK9; PDX1; RARA; NKX2-5; HDAC7
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding TLX1; ONECUT1; FOXI1; RBPJ; SOX1; SOX4; MAFB; SRF; MITF; NCOA3

    NFATC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFATC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFATC3.

    CDK6; RAF1

    Bonami, RH; Wolfle, WT; et al. NFATc2 (NFAT1) assists BCR-mediated anergy in anti-insulin B cells. MOLECULAR IMMUNOLOGY 62:321-328(2014).
    Dong, YP; Pan, QX; et al. Tumor endothelial expression of P-glycoprotein upon microvesicular transfer of TrpC5 derived from adriamycin-resistant breast cancer cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 446:85-90(2014).

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