nmnat3
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  • Official Full Name
  • nicotinamide nucleotide adenylyltransferase 3
  • Background
  • This gene encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. These enzymes use ATP to catalyze the synthesis of nicotinamide adenine dinucleotide or nicotinic acid adenine dinucleotide from nicotinamide mononucleotide or nicotinic acid mononucleotide, respectively. The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms
  • NMNAT3; nicotinamide nucleotide adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; PNAT3; NaMN adenylyltransferase 3; Nicotinate-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NMNA3_HUMAN; NMNAT 3; PNAT 3; PNAT-3; Pyridine nucleotide adenylyltransferase 3; FKSG76
Cat.#:NMNAT3-5942HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NMNAT3 Protein, GST-tagged
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Cat.#:NMNAT3-639HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NMNAT3, His-tagged
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Cat.#:NMNAT3-10749MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NMNAT3 Protein
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Cat.#:NMNAT3-1201HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NMNAT3 cell lysate
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Involved Pathway

NMNAT3 involved in several pathways and played different roles in them. We selected most pathways NMNAT3 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMNAT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Nicotinate and nicotinamide metabolism
NT5C1B; MIBP2; NUDT12; NMNAT2; NT5C2A; PNP6; NT5C2; AOX2P; AOX1; AOX3
Metabolic pathways
ATP6V1G3; ALOX12B; GNS; PPAP2C; ATP5A1; MVDA; AKR1B1; CERS1; NAT; NADK

Protein Function

NMNAT3 has several biochemical functions, for example, ATP binding, nicotinamide-nucleotide adenylyltransferase activity, nicotinate-nucleotide adenylyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMNAT3 itself. We selected most functions NMNAT3 had, and list some proteins which have the same functions with NMNAT3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein MCM2; MERTK; ATP2B1B; CDC34B; IDE; MAP2K4A; PI4K2A; PSMC4; ABCG1; PNKP
Function nicotinamide-nucleotide adenylyltransferase activity
Related Protein NMNAT1; NMNAT3; NMNAT2
Function nicotinate-nucleotide adenylyltransferase activity
Related Protein NMNAT1; NMNAT3; NMNAT2; ABL1

NMNAT3 Related Articles

Knepper, A; Schleicher, M; et al. Enhancement of the NAD(P)(H) pool in Saccharomyces cerevisiae. ENGINEERING IN LIFE SCIENCES 8:381-389(2008).
Franchetti, P; Pasqualini, M; et al. Stereoselective synthesis of nicotinamide beta-riboside and nucleoside analogs. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14:4655-4658(2004).