nod1
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  • Official Full Name
  • nucleotide-binding oligomerization domain containing 1
  • Background
  • Nod1/CARD4 is a cytosolic protein structually related to Apaf-1 and plant drug-resistance proteins that has been implicated in apoptosis and inflammatory responses to certain pathogenic bacteria. It contains an amino-terminal caspase recruitment domain (C
  • Synonyms
  • NOD1; nucleotide-binding oligomerization domain containing 1; CARD4, caspase recruitment domain family, member 4; nucleotide-binding oligomerization domain-containing protein 1; CLR7.1; NLR family; CARD domain containing 1; NLRC1; nucleotide binding olig
Cat.#:NOD1-1318HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NOD1 Protein, GST-Tagged
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Cat.#:NOD1-1769HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NOD1 protein, His & T7-tagged
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Cat.#:NOD1-3772HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NOD1 293 Cell Lysate
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Involved Pathway

NOD1 involved in several pathways and played different roles in them. We selected most pathways NOD1 participated on our site, such as Activated TLR4 signalling, Cytokine Signaling in Immune system, Epithelial cell signaling in Helicobacter pylori infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with NOD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activated TLR4 signalling
PELI3; UBE2V1; SIGIRR; CREB1; CHST13; APPB; APPA; IRAK3; MAPKAPK2B; PELI1
Cytokine Signaling in Immune system
UBE2V1; HERC5; EIF4EB; IFIT14; PEA15A; TRIM68; IFITM3; EDARADD; IFITM2; FCGR1B
Epithelial cell signaling in Helicobacter pylori infection
NFKB1; NOD1; ATP6V1F; ATP6AP1; TJP1; MAP3K14; F11R; SRC; TCIRG1; PLCG1
Immune System
RNF220; CD300LD; KIF11; TAX1BP1; POLR3G; CTLA4; TRIM10; BTR16; EIF4G2; DEFA3
Innate Immune System
CLEC5A; MGC174155; ACTR2B; DUSP3; CLEC4A; CFHL4; FCN2; CNPY3; MYO1C; MASP2
Interleukin-1 signaling
PELI2; PELI1; TNIP2; PELI3; IL1RN; NOD1; IRAK3
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
NOD1
MAP kinase activation in TLR cascade
NOD1; DUSP3B; DUSP3; TNIP2

Protein Function

NOD1 has several biochemical functions, for example, ATP binding, CARD domain binding, cysteine-type endopeptidase activator activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by NOD1 itself. We selected most functions NOD1 had, and list some proteins which have the same functions with NOD1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein NADK; PET112L; SYN1; TSSK6; PCXA; FICD; PRPS2; VMHC; ACSM3; MCM6L
Function CARD domain binding
Related Protein C9orf89; CARD9; RIPK2; NOD1; MAVS; CARD14; CARD11
Function cysteine-type endopeptidase activator activity involved in apoptotic process
Related Protein APAF1; NLRP12; CASP1; GNB2L1; RPS27L; BAD; BCL2L13; CTSH; NOD1; NLRP1
Function identical protein binding
Related Protein VPS4B; HNRNPC; ERN1; PRMT8; AHCY; MCM10; CSNK2B; HSD17B10; SHANK3; POU3F2
Function peptidoglycan binding
Related Protein NOD1; NLRP3; RNASE7; PGLYRP3; PGLYRP1; TLR2; PGLYRP2; PGLYRP4; TREM2
Function protein binding
Related Protein CORO1B; LIN28A; KCNN4; CRYBA2; MED21; ZNF41; CHMP1A; DNAJB11; MGRN1; ORAI3
Function protein homodimerization activity
Related Protein RELA; DMRTB1; NTRK1; QPRT; ERBB4; PLEK; TIMELESS; FAM109B; PDE2A; MAOB

Interacting Protein

NOD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NOD1.
RIPK2; HSP90AA1; sspH2; a8k1f4_human; b3ktt5_human; b4dyc6_human; HSPA1A; CASP9; PSMD2; FKBP5; PTGES3; CDC37; Usp19

NOD1 Related Articles

Ammerdorffer, A; Schoffelen, T; et al. Recognition of Coxiella burnetii by Toll-like Receptors and Nucleotide-Binding Oligomerization Domain-like Receptors. JOURNAL OF INFECTIOUS DISEASES 211:978-987(2015).
Xie, JS; Belosevic, M; et al. Functional characterization of receptor-interacting serine/threonine kinase 2 (RIP2) of the goldfish (Carassius auratus L.). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 48:76-85(2015).