Recombinant Human NOD1 Protein, GST-Tagged
Cat.No. : | NOD1-1318H |
Product Overview : | Human NOD1 partial ORF (AAH40339, 91 a.a. - 190 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | QQLADAYVDLRPWLLEIGFSPSLLT QSKVVVNTDPVSRYTQQLRHHLGRD SKFVLCYAQKEELLLEEIYMDTIME LVGFSNESLGSLNSLACLLDHTTGI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | NOD1 nucleotide-binding oligomerization domain containing 1 [ Homo sapiens ] |
Official Symbol : | NOD1 |
Synonyms : | NOD1; nucleotide-binding oligomerization domain containing 1; CARD4, caspase recruitment domain family, member 4; nucleotide-binding oligomerization domain-containing protein 1; CLR7.1; NLR family; CARD domain containing 1; NLRC1; nucleotide binding oligomerization domain; leucine rich repeat and CARD domain containing 1; NLR family, CARD domain containing 1; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; CARD4; |
Gene ID : | 10392 |
mRNA Refseq : | NM_006092 |
Protein Refseq : | NP_006083 |
MIM : | 605980 |
UniProt ID : | Q9Y239 |
Products Types
◆ Recombinant Protein | ||
NOD1-3895H | Recombinant Human NOD1 Protein (Ala612-Asp826), N-His tagged | +Inquiry |
NOD1-1769H | Recombinant Human NOD1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
NOD1-3772HCL | Recombinant Human NOD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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