|Official Full Name||nitric oxide synthase trafficker|
|Background||Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.|
|Synonyms||NOSTRIN; nitric oxide synthase trafficker; MGC20702; BM247; BM247 homolog; DaIP2; eNOS-trafficking inducer; mDaIP2; Nitric oxide synthase traffic inducer; NOSTN_HUMAN; RP23-431D4.2; ENOS traffic inducer; nitric oxide synthase trafficking; endothelial nitric oxide synthase traffic inducer; ortholog of mouse disabled 2 interacting proein 2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
NOSTRIN involved in several pathways and played different roles in them. We selected most pathways NOSTRIN participated on our site, such as Metabolism, Metabolism of nitric oxide, NOSTRIN mediated eNOS trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with NOSTRIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Metabolism||MED6; NUDT3B; DHCR7; PPM1L; SULT2ST1; SLC23A2; HAS3; ALDH9A1A.2; MED15; PDP2|
|Metabolism of nitric oxide||CYGB2; DDAH1; ZDHHC21; SPRB; CYGB1; NOSTRIN; GCHFR; LYPLA1; CYGB; DDAH2|
|NOSTRIN mediated eNOS trafficking||NOSTRIN|
|eNOS activation and regulation||SPRB; ZDHHC21; NOSIP; CYGB1; NOSTRIN; DDAH2; CYGB; DDAH1; LYPLA1; GCHFR|
NOSTRIN has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOSTRIN itself. We selected most functions NOSTRIN had, and list some proteins which have the same functions with NOSTRIN. You can find most of the proteins on our site.
|DNA binding||HIST1H2AC; TBR1B; SP8; DLX4B; SUPV3L1; TAL2; HJURP; HER8.2; ZBED1; ZNF581|
|protein binding||SLC6A20; PRAME; PPP3CA; WRNIP1; AKR1C1; CDC40; KLK5; ZRSR2; SALL4; DOK6|
NOSTRIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOSTRIN here. Most of them are supplied by our site. Hope this information will be useful for your research of NOSTRIN.
NOS3; FGFR1; Wasl; DNM1