NOSTRIN Protein, nitric oxide synthase trafficker


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Official Full Name nitric oxide synthase trafficker
Background Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
Synonyms NOSTRIN; nitric oxide synthase trafficker; MGC20702; BM247; BM247 homolog; DaIP2; eNOS-trafficking inducer; mDaIP2; Nitric oxide synthase traffic inducer; NOSTN_HUMAN; RP23-431D4.2; ENOS traffic inducer; nitric oxide synthase trafficking; endothelial nitric oxide synthase traffic inducer; ortholog of mouse disabled 2 interacting proein 2
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NOSTRIN-1078H Recombinant Human NOSTRIN Protein, His-tagged E.coli His
    Human NOSTRIN-3756HCL Recombinant Human NOSTRIN 293 Cell Lysate HEK293 N/A
    Human NOSTRIN-3757HCL Recombinant Human NOSTRIN 293 Cell Lysate HEK293 N/A
    Human NOSTRIN-5995H Recombinant Human NOSTRIN Protein, GST-tagged Wheat Germ GST
    Human NOSTRIN-630H Recombinant Human NOSTRIN protein, His & T7-tagged E.coli His/T7
    Mouse NOSTRIN-10789M Recombinant Mouse NOSTRIN Protein Mammalian Cell His
    Mouse Nostrin-631M Recombinant Mouse Nostrin protein, His & T7-tagged E.coli His/T7
    Rat NOSTRIN-4026R Recombinant Rat NOSTRIN Protein Mammalian Cell His
    Rat Nostrin-632R Recombinant Rat Nostrin protein, His & T7-tagged E.coli His/T7
    Zebrafish NOSTRIN-6338Z Recombinant Zebrafish NOSTRIN Mammalian Cell His

    NOSTRIN involved in several pathways and played different roles in them. We selected most pathways NOSTRIN participated on our site, such as Metabolism, Metabolism of nitric oxide, NOSTRIN mediated eNOS trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with NOSTRIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism MED6; NUDT3B; DHCR7; PPM1L; SULT2ST1; SLC23A2; HAS3; ALDH9A1A.2; MED15; PDP2
    Metabolism of nitric oxide CYGB2; DDAH1; ZDHHC21; SPRB; CYGB1; NOSTRIN; GCHFR; LYPLA1; CYGB; DDAH2
    NOSTRIN mediated eNOS trafficking NOSTRIN
    eNOS activation and regulation SPRB; ZDHHC21; NOSIP; CYGB1; NOSTRIN; DDAH2; CYGB; DDAH1; LYPLA1; GCHFR

    NOSTRIN has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOSTRIN itself. We selected most functions NOSTRIN had, and list some proteins which have the same functions with NOSTRIN. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HIST1H2AC; TBR1B; SP8; DLX4B; SUPV3L1; TAL2; HJURP; HER8.2; ZBED1; ZNF581
    protein binding SLC6A20; PRAME; PPP3CA; WRNIP1; AKR1C1; CDC40; KLK5; ZRSR2; SALL4; DOK6

    NOSTRIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOSTRIN here. Most of them are supplied by our site. Hope this information will be useful for your research of NOSTRIN.

    NOS3; FGFR1; Wasl; DNM1

    Zobel, T; Brinkmann, K; et al. Cooperative functions of the two F-BAR proteins Cip4 and Nostrin in the regulation of E-cadherin in epithelial morphogenesis. JOURNAL OF CELL SCIENCE 128:499-515(2015).
    Garcia-Tejedor, A; Gimeno-Alcaniz, JV; et al. An antihypertensive lactoferrin hydrolysate inhibits angiotensin I-converting enzyme, modifies expression of hypertension-related genes and enhances nitric oxide production in cultured human endothelial cells. JOURNAL OF FUNCTIONAL FOODS 12:45-54(2015).

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