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Official Full Name neuropeptide Y receptor Y1
Background Neuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits;a diverse range of important physiologic activities, including effects on psychomotor activity, food intake,;regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major;subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been;identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic;smooth muscle (Herzog et al., 1992 (PubMed 1321422)).
Synonyms NPY1R; neuropeptide Y receptor Y1; NPYR; neuropeptide Y receptor type 1; NPY1-R
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NPY1R-1214HCL Recombinant Human NPY1R cell lysate N/A
    Human NPY1R-1351H Recombinant Human NPY1R, GST-tagged E.coli GST
    Human NPY1R-6055H Recombinant Human NPY1R Protein Wheat Germ N/A
    Human NPY1R-6056H Recombinant Human NPY1R Protein, GST-tagged Wheat Germ GST
    Mouse NPY1R-10846M Recombinant Mouse NPY1R Protein Mammalian Cell His
    Rhesus Macaque NPY1R-3087R Recombinant Rhesus monkey NPY1R Protein, His-tagged Mammalian Cell His
    Chicken NPY1R-3179C Recombinant Chicken NPY1R Mammalian Cell His
    Zebrafish NPY1R-5917Z Recombinant Zebrafish NPY1R Mammalian Cell His
    Kit-0957 TR-FRET Progesterone Receptor Coactivator Assay Kit N/A
    Kit-1443 NPY1R CHO-K1 β-Arrestin GPCR Assay Kit N/A

    NPY1R involved in several pathways and played different roles in them. We selected most pathways NPY1R participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPY1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cAMP signaling pathway GPR119; PTGER3; MAPK1; RAC3; PIK3R1; GABBR2; FOS; ATP1A1; HCAR3; GHSR
    Neuroactive ligand-receptor interaction LPAR2; P2RX4B; NPFFR1; TAAR14H; F2; PRSS2; TRHRB; GRM8B; TAAR4; GABRR2
    Regulation of lipolysis in adipocytes AQP7; PIK3R1; TSHB; PRKG1; PIK3CD; ABHD5; PRKG2; Adcy4; IRS4; INS2

    NPY1R has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by NPY1R itself. We selected most functions NPY1R had, and list some proteins which have the same functions with NPY1R. You can find most of the proteins on our site.

    Function Related Protein
    neuropeptide Y receptor activity PRLHR2A; QRFPR; PROKR1; PROKR2; PRLHR2B; NPY8BR; NPY5R; PRLH2R; PRLHR; NPY2R
    pancreatic polypeptide receptor activity NPY1R; NPY8BR; NPY5R; PPYR1; NPY8AR
    peptide YY receptor activity NPY5R; NPY2R; PPYR1; NPY1R
    protein binding RAB6B; TAC1; TAL2; H2AFX; TCF3; BRE; GRAMD3; REXO1L1; CDC20; ATL1

    NPY1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPY1R here. Most of them are supplied by our site. Hope this information will be useful for your research of NPY1R.

    GALR2; NPY; PYY; ATP13A2; LSM7

    Xiang, Q; Wang, CL; et al. Interaction of Somatostatin receptor-2 and Neuropeptide Y receptor-1 in mice dorsal root ganglion neurons on the Pinch-nerve injury model (Retracted article. See vol. 110, pg. 273, 2013). PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 105:71-75(2013).
    Singh, S; Metz, I; et al. Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. ACTA NEUROPATHOLOGICA 125:595-608(2013).

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